C4B63_212g18

40S ribosomal protein S21

Trypanosoma cruzi Dm28c 2018 OG6: OG6_101819 OG7: OG7_0006431 135 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 135 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_40g149 ⚠ 40S ribosomal protein SA	—	OG6 Tb927.11.10790 ↔ Tb927.11.6500 OG6 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 Tb927.11.10790 ↔ Tb927.11.6500	Both
C4B63_40g129 ⚠ 40S ribosomal protein SA	—	OG6 Tb927.11.10790 ↔ Tb927.11.6500 OG6 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 Tb927.11.10790 ↔ Tb927.11.6500	Both
C4B63_40g189 ⚠ 40S ribosomal protein SA	—	OG6 Tb927.11.10790 ↔ Tb927.11.6500 OG6 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 LdBPK_110780.1 ↔ LdBPK_365350.1 OG7 Tb927.11.10790 ↔ Tb927.11.6500	Both
C4B63_7g233 ⚠ ribosomal protein S19	—	OG6 Tb927.11.6500 ↔ Tb927.4.1860 OG6 LdBPK_110780.1 ↔ LdBPK_342620.1 OG7 Tb927.11.6500 ↔ Tb927.4.1860 OG7 LdBPK_110780.1 ↔ LdBPK_342620.1	Both
C4B63_43g855c ⚠ 60S ribosomal protein L37a	—	OG6 LdBPK_110780.1 ↔ LdBPK_212190.1 OG6 Tb927.10.220 ↔ Tb927.11.6500 OG7 Tb927.10.220 ↔ Tb927.11.6500 OG7 LdBPK_110780.1 ↔ LdBPK_212190.1	Both
C4B63_48g641c ⚠ 60S ribosomal protein L37a	—	OG6 LdBPK_110780.1 ↔ LdBPK_212190.1 OG6 Tb927.10.220 ↔ Tb927.11.6500 OG7 Tb927.10.220 ↔ Tb927.11.6500 OG7 LdBPK_110780.1 ↔ LdBPK_212190.1	Both
C4B63_2g518 ⚠ 60S acidic ribosomal protein P0	—	OG6 Tb927.11.2060 ↔ Tb927.11.6500 OG7 Tb927.11.2060 ↔ Tb927.11.6500	Both
C4B63_13g236 ⚠ 40S ribosomal protein S18	—	OG6 Tb927.10.5330 ↔ Tb927.11.6500 OG7 Tb927.10.5330 ↔ Tb927.11.6500	Both
C4B63_7g241 ⚠ ribosomal protein L3	—	OG6 Tb927.11.6500 ↔ Tb927.4.1790 OG7 Tb927.11.6500 ↔ Tb927.4.1790	Both
C4B63_26g268 ⚠ 40S ribosomal protein S3	—	OG6 Tb927.11.6500 ↔ Tb927.9.6070 OG7 Tb927.11.6500 ↔ Tb927.9.6070	Both
C4B63_233g19 ⚠ ribosomal protein L15	—	OG6 Tb927.11.6500 ↔ Tb927.9.15190 OG7 Tb927.11.6500 ↔ Tb927.9.15190	Both
C4B63_6g2375c ⚠ 40S ribosomal protein S14	—	OG6 Tb927.11.6500 ↔ Tb927.6.4980 OG7 Tb927.11.6500 ↔ Tb927.6.4980	Both
C4B63_48g18 ⚠ 40S ribosomal protein S3	—	OG6 Tb927.11.6500 ↔ Tb927.9.6070 OG7 Tb927.11.6500 ↔ Tb927.9.6070	Both
C4B63_10g124 ⚠ 60S ribosomal protein L4	—	OG6 Tb927.11.6500 ↔ Tb927.3.5050 OG7 Tb927.11.6500 ↔ Tb927.3.5050	Both
C4B63_114g4 ⚠ 40S ribosomal protein S15	—	OG6 Tb927.11.6500 ↔ Tb927.7.2340 OG7 Tb927.11.6500 ↔ Tb927.7.2340	Both
C4B63_13g235 ⚠ 40S ribosomal protein S18	—	OG6 Tb927.10.5330 ↔ Tb927.11.6500 OG7 Tb927.10.5330 ↔ Tb927.11.6500	Both
C4B63_45g102 ⚠ 40S ribosomal protein S9	—	OG6 Tb927.10.5610 ↔ Tb927.11.6500 OG7 Tb927.10.5610 ↔ Tb927.11.6500	Both
C4B63_13g269 ⚠ 40S ribosomal protein S9	—	OG6 Tb927.10.5610 ↔ Tb927.11.6500 OG7 Tb927.10.5610 ↔ Tb927.11.6500	Both
C4B63_170g19 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_170g22 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_170g18 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_170g20 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_170g17 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_46g76 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_170g21 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_46g77 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
C4B63_102g86 ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_43g19c ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_168g210c ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_168g209c ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_168g35 ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_43g20c ⚠ 40S ribosomal protein S23	—	OG6 Tb927.10.1080 ↔ Tb927.11.6500 OG7 Tb927.10.1080 ↔ Tb927.11.6500	Both
C4B63_9g2155c ⚠ ribosomal protein L27	—	OG6 Tb927.11.15880 ↔ Tb927.11.6500 OG7 Tb927.11.15880 ↔ Tb927.11.6500	Both
C4B63_9g2158c ⚠ ribosomal protein L27	—	OG6 Tb927.11.15880 ↔ Tb927.11.6500 OG7 Tb927.11.15880 ↔ Tb927.11.6500	Both
C4B63_55g357c ⚠ ribosomal protein L39	—	OG6 LdBPK_110780.1 ↔ LdBPK_161220.1 OG7 LdBPK_110780.1 ↔ LdBPK_161220.1	Both
C4B63_84g49 ⚠ RNA-binding protein	—	OG6 LdBPK_110780.1 ↔ LdBPK_170610.1 OG7 LdBPK_110780.1 ↔ LdBPK_170610.1	Both
C4B63_26g228 ⚠ Eukaryotic translation initiation factor 4 ga	—	OG6 LdBPK_110780.1 ↔ LdBPK_151340.1 OG7 LdBPK_110780.1 ↔ LdBPK_151340.1	Both
C4B63_168g34 ⚠ 60S ribosomal protein L9	—	OG6 Tb927.10.1100 ↔ Tb927.11.6500 OG7 Tb927.10.1100 ↔ Tb927.11.6500	Both
C4B63_206g148c ⚠ ribosomal protein L38	—	OG6 Tb927.10.3280 ↔ Tb927.11.6500 OG7 Tb927.10.3280 ↔ Tb927.11.6500	Both
C4B63_9g2133c ⚠ 60S ribosomal protein L44	—	OG6 Tb927.11.3230 ↔ Tb927.11.6500 OG7 Tb927.11.3230 ↔ Tb927.11.6500	Both
C4B63_147g165c ⚠ ribosomal protein L38	—	OG6 Tb927.10.3280 ↔ Tb927.11.6500 OG7 Tb927.10.3280 ↔ Tb927.11.6500	Both
C4B63_24g1292c ⚠ ribosomal protein L38	—	OG6 Tb927.10.3280 ↔ Tb927.11.6500 OG7 Tb927.10.3280 ↔ Tb927.11.6500	Both
C4B63_14g560c ⚠ 60S ribosomal protein L22	—	OG6 Tb927.10.9800 ↔ Tb927.11.6500 OG7 Tb927.10.9800 ↔ Tb927.11.6500	Both
C4B63_43g4 ⚠ 60S ribosomal protein L9	—	OG6 Tb927.10.1100 ↔ Tb927.11.6500 OG7 Tb927.10.1100 ↔ Tb927.11.6500	Both
C4B63_40g124c ⚠ 60S ribosomal protein L22	—	OG6 Tb927.10.9800 ↔ Tb927.11.6500 OG7 Tb927.10.9800 ↔ Tb927.11.6500	Both
C4B63_18g144 ⚠ 60S ribosomal protein L9	—	OG6 Tb927.10.1100 ↔ Tb927.11.6500 OG7 Tb927.10.1100 ↔ Tb927.11.6500	Both
C4B63_4g355 ⚠ 60S ribosomal protein L7	—	OG7 Tb927.11.6500 ↔ Tb927.7.1730	OG7
C4B63_7g366 ⚠ ribosomal protein L14	—	OG7 Tb927.11.6500 ↔ Tb927.9.11380	OG7
C4B63_28g30 ⚠ 60S ribosomal protein L17	—	OG6 Tb927.11.4820 ↔ Tb927.11.6500 OG7 Tb927.11.4820 ↔ Tb927.11.6500	Both
C4B63_12g209 ⚠ 60S ribosomal protein L24	—	OG7 Tb927.10.5460 ↔ Tb927.11.6500	OG7

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