C4B63_63g58

Pre-rRNA-processing protein esf1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_137190 OG7: OG7_0007633 25 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 25 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g234
Signal recognition particle subunit SRP68
— Both
C4B63_107g3 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_11g99 ⚠
Putative methyltransferase NSUN6
— OG7
C4B63_23g124 ⚠
NOL1/NOP2/sun family
— OG7
C4B63_6g420 ⚠
Probable 28S rRNA (cytosine-C(5))-methyltrans
— OG7
C4B63_9g484 ⚠
5-methylcytosine rRNA methyltransferase NSUN4
— OG7
C4B63_12g396 ⚠
proteasome alpha 7 subunit
— OG7
C4B63_25g312 ⚠
proteasome alpha 3 subunit
— OG7
C4B63_2g302 ⚠
proteasome alpha 1 subunit
— OG7
C4B63_43g135 ⚠
proteasome alpha 2 subunit
— OG7
C4B63_48g135 ⚠
proteasome subunit alpha type-1
— OG7
C4B63_70g80 ⚠
proteasome alpha 7 subunit
— OG7
C4B63_7g421
coatomer alpha subunit
— Both
C4B63_44g246 ⚠
nucleolar protein
— Both
C4B63_16g108 ⚠
chaperonin/T-complex protein 1 gamma subunit
— OG6
C4B63_17g90 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_2g485 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_168g37 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_252g22 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_20g172
chaperonin alpha subunit
— OG6
C4B63_43g6 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_2g690
chaperonin alpha subunit
— OG6
C4B63_43g129 ⚠
proteasome subunit alpha type-5
— Both
C4B63_2g750
death-receptor fusion protein (DUF2428)
— Both
C4B63_63g16
chaperonin alpha subunit
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.