C4B63_6g251

DNA replication licensing factor MCM6
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101983 OG7: OG7_0001163 16 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 16 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_80g20 ⚠
DNA replication licensing factor MCM3(fragmen
— OG6
C4B63_80g19 ⚠
DNA replication licensing factor MCM7
— OG6
C4B63_6g108
DNA replication licensing factor MCM2
— OG6
C4B63_27g182
DNA replication licensing factor MCM4
— OG6
C4B63_9g314
DNA replication licensing factor MCM3
— OG6
C4B63_28g120
DNA replication licensing factor MCM5
— OG6
C4B63_23g81
DNA replication complex GINS protein SLD5
— OG6
C4B63_8g558
Mini-chromosome maintenance complex-binding p
— OG6
C4B63_26g195
DNA replication complex GINS protein PSF1
— OG6
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_303g14 ⚠
DNA replication licensing factor MCM8
— OG6
C4B63_303g13 ⚠
DNA replication licensing factor MCM8(fragmen
— OG6
C4B63_14g239 ⚠
DNA replication licensing factor MCM8
— OG6
C4B63_12g246
conserved hypothetical protein
— OG6
C4B63_101g31
chromatin assembly factor 1 subunit B
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.