CFAC1_190020600

HECT-domain (ubiquitin-transferase), putative
Crithidia fasciculata strain Cf-Cl OG6: OG6_102181 OG7: OG7_0002947 159 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 159 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_300030200 ⚠
replication factor A, 51kDa subunit, putative
— OG7
CFAC1_020014700 ⚠
Vta1 like, putative
— OG7
CFAC1_290042900 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
CFAC1_090009400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
CFAC1_270045300 ⚠
dihydrouridine synthase (Dus), putative
— OG7
CFAC1_280077100 ⚠
replication factor C, subunit 5, putative
— OG7
CFAC1_260050500 ⚠
replication factor C, subunit 2, putative
— OG7
CFAC1_250011700 ⚠
dihydrouridine synthase domain protein-like p
— OG7
CFAC1_120013100 ⚠
aspartate carbamoyltransferase, putative
— OG7
CFAC1_180018600 ⚠
hypothetical protein, conserved
— OG7
CFAC1_230046600 ⚠
replication factor C, subunit 4, putative
— OG7
CFAC1_090011900 ⚠
ATPase family associated with various cellula
— OG7
CFAC1_300082900 ⚠
replication factor C, subunit 3, putative
— OG7
CFAC1_260026300 ⚠
co-chaperone GrpE, putative
— OG7
CFAC1_260055800 ⚠
homoserine kinase, putative
— OG7
CFAC1_230028400 ⚠
ras-like small GTPases, putative
— OG7
CFAC1_020008100 ⚠
50S ribosome-binding GTPase, putative
— OG7
CFAC1_300104100 ⚠
GTP-binding protein, putative
— OG7
CFAC1_020011400 ⚠
GTPase, putative
— OG7
CFAC1_290022700 ⚠
guanine nucleotide-binding protein-like prote
— OG7
CFAC1_270049800 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
CFAC1_150010900 ⚠
hypothetical protein, conserved
— OG7
CFAC1_050006700 ⚠
LSM domain containing protein, putative
— OG7
CFAC1_290013300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_230016000 ⚠
LSM domain containing protein, putative
— OG7
CFAC1_050013400 ⚠
ubiquitin activating enzyme, putative
— OG7
CFAC1_190020400 ⚠
small nuclear ribonucleoprotein, putative
— OG7
CFAC1_290013400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_300096100 ⚠
sm-f snRNP core complex protein, putative
— OG7
CFAC1_090008200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_260032300 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
CFAC1_280045400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_250039200 ⚠
cyclin-e binding protein 1-like protein
— OG7
CFAC1_270062200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_290048400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
CFAC1_130010200 ⚠
chromatin binding protein, putative
— OG7
CFAC1_290071800 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_240045700 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_120015300 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_300062000 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_050019100 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
CFAC1_260029600 ⚠
p22 protein precursor, putative
— OG7
CFAC1_140020900 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
CFAC1_040020100 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
CFAC1_100012800 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
CFAC1_040011200 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
CFAC1_290010000 ⚠
pseudouridylate synthase-like protein
— OG7
CFAC1_290031100 ⚠
tRNA pseudouridine synthase, putative
— OG7
CFAC1_240023200 ⚠
Mitochondrial glycoprotein, putative
— OG7
CFAC1_140027600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.