CFAC1_210042800

tyrosyl-DNA phosphodiesterase 1
Crithidia fasciculata strain Cf-Cl OG6: OG6_101894 OG7: OG7_0006309 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_120010300 ⚠
tubulin tyrosine ligase, putative
— OG7
CFAC1_070008100
TatD related DNase, putative
— Both
CFAC1_270045300 ⚠
dihydrouridine synthase (Dus), putative
— Both
CFAC1_040013400 ⚠
zinc-binding dehydrogenase-like protein
— OG7
CFAC1_040013300 ⚠
zinc binding dehydrogenase-like protein
— OG7
CFAC1_290042900 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
CFAC1_090009400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
CFAC1_250011700 ⚠
dihydrouridine synthase domain protein-like p
— OG7
CFAC1_160022400 ⚠
hypothetical protein, conserved
— OG7
CFAC1_200008900 ⚠
Isochorismatase family, putative
— OG7
CFAC1_190043100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
CFAC1_240018700 ⚠
Metallo-beta-lactamase superfamily, putative
— Both
CFAC1_200008800 ⚠
Isochorismatase family, putative
— OG7
CFAC1_210028800 ⚠
tubulin-tyrosine ligase-like protein
— OG7
CFAC1_010006200 ⚠
ribonuclease mar1
— OG7
CFAC1_140010200 ⚠
tubulin tyrosine ligase protein, putative
— OG7
CFAC1_130010000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
CFAC1_300100600 ⚠
tubulin tyrosine ligase, putative
— OG7
CFAC1_100024100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
CFAC1_260046300 ⚠
tubulin-tyrosine ligase-like protein
— OG7
CFAC1_010006600
DNA ligase I, ATP-dependent (dnl1), putative
— OG7
CFAC1_290065500 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
CFAC1_150016600 ⚠
ubiquitin-activating enzyme E1, putative
— Both
CFAC1_220041300
Thiamin pyrophosphokinase, vitamin B1 binding
— Both
CFAC1_260023700
N-acetyltransferase B complex (NatB) non cata
— Both
CFAC1_300033800
hypothetical protein, conserved
— Both
CFAC1_200009000 ⚠
mitochondrial associated ribonuclease, putati
— Both
CFAC1_080007000
metallo-peptidase, Clan ME, Family M16C
— Both
CFAC1_260042200
C2H2 type zinc-finger (2 copies), putative
— Both
CFAC1_020021600
3-mercaptopyruvate sulfurtransferase
— Both
CFAC1_060012700
kinase-like protein
— Both
CFAC1_300080900 ⚠
ubiquitin-activating enzyme E1, putative
— Both
CFAC1_240043700
TFIIB zinc-binding, putative
— Both
CFAC1_160022500 ⚠
hypothetical protein, conserved
— Both
CFAC1_270044900 ⚠
peptidase m20/m25/m40 family-like protein
— Both
CFAC1_280028300 ⚠
peptidase m20/m25/m40 family-like protein
— Both
CFAC1_180014700 ⚠
tubulin-tyrosine ligase, putative
— Both
CFAC1_070007900
Ubiquitin-like domain containing protein, put
— Both
CFAC1_230042800
WD domain, G-beta repeat, putative
— Both
CFAC1_160014500
casein kinase II, alpha chain, putative
— OG6
CFAC1_130015800 ⚠
Programmed cell death protein 2, C-terminal p
— Both
CFAC1_300030200
replication factor A, 51kDa subunit, putative
— Both
CFAC1_240018800 ⚠
Beta-lactamase superfamily domain containing
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.