CFAC1_280071300

homocysteine S-methyltransferase, putative
Crithidia fasciculata strain Cf-Cl OG6: OG6_102920 OG7: OG7_0003584 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_270058800 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
CFAC1_190030000
rab11B GTPase, putative
— OG6
CFAC1_300023800 ⚠
haloacid dehalogenase-like hydrolase-like pro
— Both
CFAC1_300023900 ⚠
haloacid dehalogenase-like hydrolase-like pro
— Both
CFAC1_300089400
calmodulin-like protein
— OG6
CFAC1_280068200
OTU-like cysteine protease, putative
— Both
CFAC1_200014200
hypothetical protein, conserved
— OG7
CFAC1_280034100 ⚠
hypothetical protein, conserved
— OG7
CFAC1_260032600 ⚠
calcium-binding protein, putative
— OG7
CFAC1_220026200 ⚠
hypothetical protein, conserved
— OG7
CFAC1_170010000 ⚠
hypothetical protein, conserved
— OG7
CFAC1_040014000 ⚠
Pyridoxal-dependent decarboxylase, pyridoxal
— OG7
CFAC1_190041400
hypothetical protein, conserved
— OG7
CFAC1_270058700 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
CFAC1_300023700 ⚠
Cof-like hydrolase/HAD hydrolase, family IIB,
— Both
CFAC1_270058500 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
CFAC1_300024400 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
CFAC1_300024500 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
CFAC1_190042900 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_300023600 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
CFAC1_300073100 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_010007600 ⚠
ubiquitin hydrolase, putative
— OG7
CFAC1_300023500 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
CFAC1_090020400 ⚠
MSP (Major sperm protein) domain containing p
— OG7
CFAC1_260022200 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
CFAC1_280068800 ⚠
disgorgin, putative
— OG7
CFAC1_280068900 ⚠
rab-like GTPase activating protein, putative
— OG7
CFAC1_180018200
hypothetical protein, conserved
— OG7
CFAC1_300024100 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
CFAC1_270058600 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— Both
CFAC1_270058300 ⚠
ferredoxin 2fe-2s-like protein
— Both
CFAC1_290018600 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— Both
CFAC1_270058400 ⚠
ferredoxin, 2fe-2s-like protein
— Both
CFAC1_100013200 ⚠
serine/threonine protein phosphatase, putativ
— OG6
CFAC1_020007100 ⚠
phosphoprotein phosphatase, putative
— OG6
CFAC1_010005700
PITH domain containing protein, putative
— Both
CFAC1_240035700
hypothetical protein, conserved
— Both
CFAC1_290063200
D-Tyr-tRNA(Tyr) deacylase, putative
— Both
CFAC1_190030400
Cation efflux family, putative
— Both
CFAC1_300023400 ⚠
HAD hydrolase, family IIB, putative
— Both
CFAC1_120026400
hypothetical protein, conserved
— Both
CFAC1_300022700 ⚠
HAD hydrolase, family IIB, putative
— Both
CFAC1_200030000
Leucine-rich repeat, putative
— Both
CFAC1_290059000 ⚠
hypothetical protein, conserved
— Both
CFAC1_260022000
mitogen-activated protein kinase, putative
— OG6
CFAC1_160015600 ⚠
diaminopimelate decarboxylase, putative
— OG6
CFAC1_010008700 ⚠
ornithine decarboxylase, putative
— Both
CFAC1_150020100
SET domain containing protein, putative
— OG6
CFAC1_280070100 ⚠
Sucrase/ferredoxin-like, putative
— Both
CFAC1_270008900 ⚠
Sucrase/ferredoxin-like, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.