CFAC1_290029300

mitochondrial malate dehydrogenase
Crithidia fasciculata strain Cf-Cl OG6: OG6_101212 OG7: OG7_0004751 77 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 77 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_030014700 ⚠
spermidine synthase
— Both
CFAC1_170031300 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_230044700 ⚠
reductase, putative
— OG7
CFAC1_210039300 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
CFAC1_230008300 ⚠
glutathionylspermidine synthase, putative
— OG7
CFAC1_210040100 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
CFAC1_190036500 ⚠
cytochrome-b5 reductase, putative
— OG7
CFAC1_260052500 ⚠
chaperonin HSP60/CNP60, putative
— OG7
CFAC1_010015300 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_010015100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_130008500 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
CFAC1_170031200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_110019900 ⚠
Sodium/hydrogen exchanger family, putative
— Both
CFAC1_170031400 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_010015200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_010015000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_010015400 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_260034200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
CFAC1_290014800 ⚠
amidohydrolase, putative
— OG6
CFAC1_050016100 ⚠
oligopeptidase b
— Both
CFAC1_220017300 ⚠
hypothetical protein, conserved
— OG7
CFAC1_060019100 ⚠
ecotin, putative
— OG7
CFAC1_060016400 ⚠
ecotin, putative
— OG7
CFAC1_100023600 ⚠
hypothetical protein, conserved
— OG7
CFAC1_240024600 ⚠
ser/thr protein phosphatase, putative
— OG7
CFAC1_240029600 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
CFAC1_300026400 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
CFAC1_050014000 ⚠
eukaryotic initiation factor 4a, putative
— OG7
CFAC1_280049800 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
CFAC1_220035300 ⚠
Metallopeptidase family M24, putative
— OG7
CFAC1_220024900 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
CFAC1_280077500 ⚠
prolyl oligopeptidase, putative
— OG7
CFAC1_050014400 ⚠
prolyl oligopeptidase, putative
— OG7
CFAC1_290064600 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
CFAC1_150012500 ⚠
trypanothione synthetase, putative
— OG7
CFAC1_290006800 ⚠
Phosphoribosyl transferase domain containing
— OG7
CFAC1_220039400 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
CFAC1_300084800 ⚠
Replication factor A protein 3, putative
— OG7
CFAC1_160017900 ⚠
cytochrome c oxidase subunit V, putative
— OG7
CFAC1_060022300 ⚠
cytochrome-b5 reductase, putative
— Both
CFAC1_280076400 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
CFAC1_260032700 ⚠
pyridoxal kinase, putative
— Both
CFAC1_300045600 ⚠
cytosolic malate dehydrogenase
— Both
CFAC1_210035400 ⚠
trypanothione synthetase, putative
— Both
CFAC1_250031000 ⚠
chaperonin HSP60, mitochondrial precursor, pu
— Both
CFAC1_240014900 ⚠
NADH-cytochrome b5 reductase, putative
— Both
CFAC1_240015000 ⚠
NADH-cytochrome b5 reductase, putative
— Both
CFAC1_200035900 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— Both
CFAC1_210017700 ⚠
triosephosphate isomerase
— Both
CFAC1_290006900 ⚠
adenine phosphoribosyltransferase
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.