LAEL147_000543300

hypothetical protein, conserved
Leishmania aethiopica L147 OG6: OG6_200044 OG7: OG7_0033976 15 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 15 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000167100
hypothetical protein, conserved
— Both
LAEL147_000691900
ATP synthase regulation protein NCA2, putativ
— Both
LAEL147_000272600 ⚠
chaperone DNAJ protein, putative
— Both
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000841200 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000028500
hypothetical protein, conserved
— OG7
LAEL147_000437700 ⚠
DnaJ domain containing protein, putative
— OG7
LAEL147_000101800
adaptor complex protein (AP) 3 delta subunit
— OG7
LAEL147_000244500
LSM domain containing protein, putative
— OG7
LAEL147_000682000
Tetratricopeptide repeats, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.