LAEL147_000700200

46 kD virulence factor
Leishmania aethiopica L147 OG6: OG6_478642 OG7: OG7_0024626 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000677800 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LAEL147_000038500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000395400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000481200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000727200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000039000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000864200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000035100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000436900 ⚠
Axonemal dynein light chain, putative
— OG7
LAEL147_000382200 ⚠
dynein arm light chain, putative
— OG7
LAEL147_000324000 ⚠
dynein arm light chain, putative
— OG7
LAEL147_000163100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000276100 ⚠
fibrillarin, putative
— OG7
LAEL147_000842600 ⚠
fibrillarin
— OG7
LAEL147_000262900 ⚠
tubulin-specific chaperone, putative
— OG7
LAEL147_000284000 ⚠
CAP-Gly domain containing protein, putative
— OG7
LAEL147_000168000 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000200600 ⚠
tc40 antigen-like
— OG7
LAEL147_000068800 ⚠
paraflagellar rod protein, putative
— OG7
LAEL147_000053400 ⚠
Axonemal dynein light chain, putative
— OG7
LAEL147_000295300 ⚠
Midasin, putative
— OG7
LAEL147_000419400 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LAEL147_000320400 ⚠
Domain of unknown function (DUF3819)/CCR4-Not
— OG7
LAEL147_000284700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000051800 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LAEL147_000317300 ⚠
Tetratricopeptide repeat, putative
— OG7
LAEL147_000199100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000219800 ⚠
protein kinase, putative
— OG7
LAEL147_000731300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LAEL147_000174700 ⚠
protein kinase A regulatory subunit, putative
— OG7
LAEL147_000175800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000063400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LAEL147_000101000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LAEL147_000327600 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000155100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000074300 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000254500 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000826800 ⚠
exoribonuclease 2, putative
— OG7
LAEL147_000038600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000682000 ⚠
Tetratricopeptide repeats, putative
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000511400 ⚠
gamma-tubulin complex subunit, putative
— OG7
LAEL147_000551500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000624000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000546700 ⚠
MATH domain containing protein, putative
— OG7
LAEL147_000330500 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.