LAEL147_000727700

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain/Domain of unknown function (DUF1981), putative
Leishmania aethiopica L147 OG6: OG6_154458 OG7: OG7_0001170 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000053900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000774100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000878400 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000349700 ⚠
CCR4 associated factor, putative
— OG7
LAEL147_000445600 ⚠
microtubule-associated protein, putative
— OG7
LAEL147_000587500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000667400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000886800 ⚠
elks delta-like protein
— OG7
LAEL147_000777700 ⚠
Transport protein Trs120 or TRAPPC9, TRAPP II
— OG7
LAEL147_000563200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000477300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000101000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LAEL147_000276100 ⚠
fibrillarin, putative
— OG7
LAEL147_000320400 ⚠
Domain of unknown function (DUF3819)/CCR4-Not
— OG7
LAEL147_000523100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000819600 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LAEL147_000794500 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LAEL147_000199100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000142500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000038500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000200600 ⚠
tc40 antigen-like
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000623400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000685000 ⚠
Lissencephaly type-1-like homology motif cont
— OG7
LAEL147_000351700 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000262900 ⚠
tubulin-specific chaperone, putative
— OG7
LAEL147_000220100 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LAEL147_000161800 ⚠
translation initiation factor EIF-2b alpha su
— OG7
LAEL147_000363700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000163100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000038600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000711900 ⚠
elongation factor 1-beta
— OG7
LAEL147_000245800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000141500 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LAEL147_000168000 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000416900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000214900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000712200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000376200 ⚠
dynein intermediate-chain-like protein
— OG7
LAEL147_000694800 ⚠
dynein intermediate chain, putative
— OG7
LAEL147_000515400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000203600 ⚠
WD40 repeats, putative
— OG7
LAEL147_000384400 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LAEL147_000254500 ⚠
5'-3' exonuclease, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.