LAMA_000558900

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_139904 OG7: OG7_0042890 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000779800
hypothetical protein, conserved
— Both
LAMA_000162900
hypothetical protein, conserved
— OG7
LAMA_000251000 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000576300 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000062700 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000328400 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000480700 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000298600 ⚠
Dynein light chain type 1, putative
— OG7
LAMA_000537000
hypothetical protein, conserved
— Both
LAMA_000403400
PCI domain/26S proteasome regulatory subunit
— Both
LAMA_000099300
von Willebrand factor type A domain/Ubiquitin
— Both
LAMA_000185900
Proteasomal ATPase OB C-terminal domain/AAA d
— OG6
LAMA_000423400
Proteasomal ATPase OB C-terminal domain/ATPas
— OG6
LAMA_000656600 ⚠
Dynein light chain type 1, putative
— Both
LAMA_000798100
hypothetical protein, conserved
— Both
LAMA_000036700
26S proteasome regulatory subunit RPN6 N-term
— Both
LAMA_000424200
hypothetical protein, conserved
— Both
LAMA_000422900
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000300200
PCI domain containing protein, putative
— Both
LAMA_000666300
CSN8/PSMD8/EIF3K family, putative
— Both
LAMA_000203500
Proteasomal ATPase OB C-terminal domain/AAA d
— OG6
LAMA_000045600
Proteasomal ATPase OB C-terminal domain/Holli
— OG6
LAMA_000683300
26S proteasome subunit RPN7/PCI domain contai
— Both
LAMA_000350900
Proteasomal ATPase OB C-terminal domain/Holli
— OG6
LAMA_000735800
JAB1/Mov34/MPN/PAD-1 ubiquitin protease/Proka
— Both
LAMA_000537200
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.