LINF_360073700

homocysteine S-methyltransferase - putative
Leishmania infantum JPCM5 OG6: OG6_102920 OG7: OG7_0003584 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_330011600 ⚠
SET domain containing protein - putative
— OG7
LINF_320034800
hypothetical protein - conserved
— Both
LINF_350044300
calmodulin-like protein
— OG6
LINF_360070100
OTU-like cysteine protease - putative
— Both
LINF_230015700 ⚠
SET domain containing protein - putative
— OG7
LINF_360039400 ⚠
hypothetical protein - conserved
— OG7
LINF_080013200 ⚠
SET domain containing protein - putative
— OG7
LINF_060015800 ⚠
MYND finger/SET domain containing protein - p
— OG7
LINF_240023500 ⚠
SET domain containing protein - putative
— OG7
LINF_360079700 ⚠
hypothetical protein
— OG7
LINF_270006500 ⚠
SET domain containing protein - putative
— OG7
LINF_120017200 ⚠
MYND finger/SET domain containing protein - p
— OG7
LINF_190008300 ⚠
hypothetical protein - conserved
— OG7
LINF_340016800 ⚠
SET domain/Tetratricopeptide repeat - putativ
— OG7
LINF_360070700 ⚠
rab-like GTPase activating protein - putative
— Both
LINF_060007500 ⚠
hypothetical protein - conserved
— OG7
LINF_300018000 ⚠
calcium-binding protein - putative
— OG7
LINF_310033400 ⚠
ferredoxin - 2fe-2s-like protein
— OG7
LINF_310033300 ⚠
ferredoxin - 2fe-2s-like protein
— OG7
LINF_310007800 ⚠
hypothetical protein - conserved
— OG7
LINF_170019400 ⚠
MSP (Major sperm protein) domain containing p
— OG7
LINF_120007000 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_280019600 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LINF_280019200 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_280019300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_360070600 ⚠
disgorgin - putative
— OG7
LINF_120007900
ornithine decarboxylase - putative
— Both
LINF_120005100
PITH domain-containing protein
— Both
LINF_260015500 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— Both
LINF_310033200 ⚠
ferredoxin - 2fe-2s-like protein
— Both
LINF_310033100 ⚠
ferredoxin 2fe-2s-like protein
— Both
LINF_090010600 ⚠
serine/threonine protein phosphatase - putat
— OG6
LINF_050005900 ⚠
phosphoprotein phosphatase - putative
— OG6
LINF_350014600
hypothetical protein - conserved
— Both
LINF_200015700
hypothetical protein - conserved
— Both
LINF_230005000
hypothetical protein - conserved
— Both
LINF_340040600
D-Tyr-tRNA(Tyr) deacylase - putative
— Both
LINF_320024500
Cation efflux family - putative
— Both
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— Both
LINF_160020900
hypothetical protein - conserved
— Both
LINF_290029800
leucine-rich repeat-containing protein
— Both
LINF_340036200 ⚠
EF-hand domain pair/EF-hand domain/EF hand -
— Both
LINF_230016000 ⚠
SET domain containing protein - putative
— Both
LINF_300008700
mitogen-activated protein kinase - putative
— OG6
LINF_360071800 ⚠
Sucrase/ferredoxin-like - putative
— Both
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_340018300
Uncharacterised ACR - YggU family COG1872 - p
— Both
LINF_350058200
Homeobox associated leucine zipper - putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.