LPAL13_000050300

Temperature dependent protein affecting M2 dsRNA replication, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_143822 OG7: OG7_0013037 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_100017200 ⚠
hypothetical protein
— OG7
LPAL13_100017300 ⚠
PAB1-binding protein , putative
— OG7
LPAL13_260009700 ⚠
DNA polymerase sigma-like protein
— OG7
LPAL13_150006400 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LPAL13_270006800 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LPAL13_340015400 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LPAL13_150014400 ⚠
protein phosphatase 2A regulatory subunit, pu
— OG7
LPAL13_180017300 ⚠
Protein of unknown function (DUF3648), putati
— OG7
LPAL13_200035800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LPAL13_010008900 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
LPAL13_110011700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000025800 ⚠
translation-associated element 2, putative
— OG7
LPAL13_210015200 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LPAL13_340015200 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LPAL13_350049100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LPAL13_040010900 ⚠
Nucleotidyltransferase domain/Cid1 family pol
— OG7
LPAL13_350049200 ⚠
hypothetical protein
— OG7
LPAL13_320005200 ⚠
nuclear segregation protein, putative
— OG7
LPAL13_100016600 ⚠
Eukaryotic translation initiation factor 4 ga
— OG7
LPAL13_150015400 ⚠
glutamate dehydrogenase
— OG7
LPAL13_000033700 ⚠
Beta-lactamase superfamily domain containing
— OG7
LPAL13_090017200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_090017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_150010700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180013700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180013600 ⚠
zinc finger containing protein, putative
— OG7
LPAL13_330038300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_060007000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_070011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_170007300 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_350015700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350071500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350066300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190012200 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LPAL13_350067500 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG7
LPAL13_340038400 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LPAL13_320013200 ⚠
cyclin 9, putative
— OG7
LPAL13_350032000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200006700 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_260009800 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_280006400 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LPAL13_050006500 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_300006700 ⚠
leucine-rich repeat protein, putative
— OG7
LPAL13_280035500 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LPAL13_090014300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_040011600 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
LPAL13_080006000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280021100 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LPAL13_150006600 ⚠
zinc finger (CCCH type) protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.