LPAL13_140016700

'Cold-shock' DNA-binding domain containing protein, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147036 OG7: OG7_0042945 71 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 71 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_190005500 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LPAL13_350080800 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LPAL13_130020000 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LPAL13_130017000 ⚠ AAA domain/Dpy-30 motif containing protein, p	—	OG7 TCSYLVIO_000435 ↔ TCSYLVIO_010606	OG7
LPAL13_330008100 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LPAL13_000036300 ⚠ ABC transport system ATP-binding protein, put	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LPAL13_000015500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	OG7
LPAL13_130005900 ⚠ mitochondrial DNA polymerase I protein B, put	—	OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	OG7
LPAL13_030013900 ⚠ MORN repeat, putative	—	OG7 TCSYLVIO_001987 ↔ TCSYLVIO_010606	OG7
LPAL13_270019900 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LPAL13_120005200 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	Both
LPAL13_260005200 brix domain containing-like protein	—	OG6 TCSYLVIO_000956 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000956 ↔ TCSYLVIO_010606	Both
LPAL13_320041000 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_005312 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	Both
LPAL13_280015600 oxidoreductase-like protein	—	OG6 TCSYLVIO_002566 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_002566 ↔ TCSYLVIO_010606	Both
LPAL13_130019700 ⚠ mitochondrial DNA polymerase I protein D, put	—	OG6 TCSYLVIO_003485 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	Both
LPAL13_280006300 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
LPAL13_080012300 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LPAL13_060014000 lipin, putative	—	OG6 TCSYLVIO_001856 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001856 ↔ TCSYLVIO_010606	Both
LPAL13_120006800 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LPAL13_200056600 ⚠ N-ethylmaleimide-sensitive factor, putative	—	OG7 Tb927.11.1680 ↔ Tb927.7.3810	OG7
LPAL13_200044400 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LPAL13_260008700 ⚠ RET2, RNA editing complex MP57	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LPAL13_140014500 ⚠ RNA editing 3' terminal uridylyl transferase	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LPAL13_340021800 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LPAL13_280013500 ⚠ RNA polymerase I	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LPAL13_350023000 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
LPAL13_030010800 hypothetical protein, conserved	—	OG7 TCSYLVIO_008440 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010263 ↔ TCSYLVIO_010606	OG7
LPAL13_340054800 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_005678 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LPAL13_340028700 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LPAL13_270020000 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LPAL13_210025100 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LPAL13_270007400 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LPAL13_140008100 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LPAL13_350022400 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LPAL13_350038200 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	OG7
LPAL13_340044800 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LPAL13_320037700 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LPAL13_260012900 hypothetical protein, conserved	—	OG6 Tb927.7.1100 ↔ Tb927.7.3810 OG7 Tb927.7.1100 ↔ Tb927.7.3810	Both
LPAL13_330027400 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LPAL13_350063900 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LPAL13_180011100 hypothetical protein, conserved	—	OG6 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG6 TCSYLVIO_006209 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006209 ↔ TCSYLVIO_010606	Both
LPAL13_190005300 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_010606	Both
LPAL13_230011900 hypothetical protein, conserved	—	OG6 TCSYLVIO_000050 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000050 ↔ TCSYLVIO_010606	Both
LPAL13_000009900 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_010606	Both
LPAL13_030011000 ⚠ DEAD/DEAH box helicase/Helicase conserved C-t	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	Both
LPAL13_220018400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
LPAL13_270030200 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LPAL13_300034900 kinesin, putative	—	OG6 TCSYLVIO_003336 ↔ TCSYLVIO_010606	OG6
LPAL13_330031500 glycosyl hydrolase-like protein	—	OG6 TCSYLVIO_003461 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003461 ↔ TCSYLVIO_010606	Both
LPAL13_210024100 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both

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