LPAL13_170013600

guanosine monophosphate reductase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100534 OG7: OG7_0002928 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_270009200 ⚠
KRI1-like family/KRI1-like family C-terminal,
— Both
LPAL13_020006100 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LPAL13_250018500 ⚠
hypothetical protein, conserved
— OG6
LPAL13_070011100 ⚠
hypothetical protein, conserved
— OG6
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG6
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LPAL13_320036200 ⚠
Prefoldin subunit, putative
— OG6
LPAL13_270017700 ⚠
cysteine desulfurase, putative
— Both
LPAL13_110012800 ⚠
PUB domain containing protein, putative
— OG6
LPAL13_110009900 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
LPAL13_340005400 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
LPAL13_250017700 ⚠
ATPase beta subunit, putative
— OG6
LPAL13_000008000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG6
LPAL13_340017300 ⚠
hypothetical protein, conserved
— Both
LPAL13_160019000 ⚠
EMG1/NEP1 methyltransferase, putative
— Both
LPAL13_030011000 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG6
LPAL13_300033900 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
LPAL13_300011700 ⚠
ribosome biogenesis regulatory protein (RRS1)
— Both
LPAL13_340022600 ⚠
Eukaryotic rRNA processing protein EBP2, puta
— Both
LPAL13_260005200 ⚠
brix domain containing-like protein
— Both
LPAL13_310032300 ⚠
acetoin dehydrogenase e3 component-like prote
— OG6
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— OG6
LPAL13_110012500 ⚠
Leucine Rich repeat, putative
— OG6
LPAL13_020008000 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG6
LPAL13_030013200 ⚠
peter pan protein, putative
— Both
LPAL13_180013400 ⚠
5-oxoprolinase, putative
— OG6
LPAL13_270015200 ⚠
hypothetical protein, conserved
— Both
LPAL13_320013100 ⚠
RNA binding protein, putative
— Both
LPAL13_270030800 ⚠
EMG1/NEP1 methyltransferase, putative
— OG7
LPAL13_330038700 ⚠
hypothetical protein, conserved
— OG6
LPAL13_270015400 ⚠
hypothetical protein, conserved
— Both
LPAL13_200065000 ⚠
ribosome biogenesis protein, putative
— Both
LPAL13_020010600 ⚠
Nop14-like family, putative
— OG6
LPAL13_250018000 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_310027100 ⚠
ARM-like helical domain-containing protein
— OG6
LPAL13_260012900 ⚠
hypothetical protein, conserved
— OG6
LPAL13_340021700 ⚠
casein kinase II, putative
— OG6
LPAL13_210014400 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG6
LPAL13_280026800 ⚠
p21-C-terminal region-binding protein, putati
— OG6
LPAL13_290021700 ⚠
MORN repeat, putative
— OG6
LPAL13_290026000 ⚠
aspartyl aminopeptidase, putative
— OG6
LPAL13_330036600 ⚠
translation initiation factor IF-2, putative
— OG6
LPAL13_340032200 ⚠
IQ calmodulin-binding motif containing protei
— OG6
LPAL13_230010900 ⚠
5'-AMP-activated protein kinase beta subunit,
— OG6
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG6
LPAL13_350019800 ⚠
hypothetical protein, conserved
— OG6
LPAL13_340036900 ⚠
RNA-binding protein, putative
— OG6
LPAL13_310020200 ⚠
hypothetical protein
— OG6
LPAL13_310020100 ⚠
Leucine Rich repeat, putative
— OG6
LPAL13_260019500 ⚠
farnesyltransferase beta subunit
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.