LPAL13_180010700

DNA-directed RNA polymerase II/III subunit, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101049 OG7: OG7_0005341 48 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 48 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_200013700 ⚠ DNA-directed RNA polymerase III subunit, puta	—	OG6 LdBPK_180780.1 ↔ LdBPK_340940.1 OG6 Tb927.10.13320 ↔ Tb927.4.3510 OG7 LdBPK_180780.1 ↔ LdBPK_340940.1 OG7 Tb927.10.13320 ↔ Tb927.11.200 +1 more	Both
LPAL13_280028100 ⚠ DNA-directed RNA polymerase-like protein	—	OG6 Tb927.10.13320 ↔ Tb927.11.8890 OG7 LdBPK_180780.1 ↔ LdBPK_271450.1 OG7 Tb927.10.13320 ↔ Tb927.11.8890 OG7 Tb927.10.13320 ↔ Tb927.11.2200	Both
LPAL13_250006600 ⚠ DNA-directed RNA polymerase I subunit, putati	—	OG6 Tb927.10.13320 ↔ Tb927.11.200 OG7 LdBPK_180780.1 ↔ LdBPK_340940.1 OG7 Tb927.10.13320 ↔ Tb927.11.200 OG7 Tb927.10.13320 ↔ Tb927.4.3510	Both
LPAL13_270022500 ⚠ DNA-directed RNA polymerase II-like protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_271450.1 OG6 Tb927.10.13320 ↔ Tb927.11.2200 OG7 LdBPK_180780.1 ↔ LdBPK_271450.1 OG7 Tb927.10.13320 ↔ Tb927.11.8890 +1 more	Both
LPAL13_270006800 ⚠ WW domain/Zinc finger C-x8-C-x5-C-x3-H type (	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
LPAL13_030010800 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006204 ↔ TCSYLVIO_009417	OG7
LPAL13_310006600 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG6 Tb927.10.13320 ↔ Tb927.4.3810 OG7 Tb927.10.13320 ↔ Tb927.11.630 OG7 Tb927.10.13320 ↔ Tb927.4.3810	Both
LPAL13_130014600 ⚠ DNA-directed RNA polymerase I subunit, putati	—	OG6 Tb927.10.13320 ↔ Tb927.3.1250 OG7 Tb927.10.13320 ↔ Tb927.3.1250	Both
LPAL13_250019000 ⚠ RNA-binding protein RBP10, putative	—	OG6 Tb927.10.13320 ↔ Tb927.3.1250 OG7 Tb927.10.13320 ↔ Tb927.3.1250	Both
LPAL13_250011200 ⚠ RNA polymerase I second largest subunit, puta	—	OG6 Tb927.10.13320 ↔ Tb927.11.630 OG7 Tb927.10.13320 ↔ Tb927.11.630 OG7 Tb927.10.13320 ↔ Tb927.4.3810	Both
LPAL13_350050700 ⚠ DNA-directed RNA polymerase I subunit, putati	—	OG6 Tb927.10.13320 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13310 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.10420	Both
LPAL13_200054000 ⚠ DNA-directed RNA polymerase 2, RPB12 subunit,	—	OG6 Tb927.1.1170 ↔ Tb927.10.13320 OG7 Tb927.1.1170 ↔ Tb927.10.13320	Both
LPAL13_110016800 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001614 ↔ TCSYLVIO_006204 OG7 TCSYLVIO_001614 ↔ TCSYLVIO_006204	Both
LPAL13_340015400 ⚠ Zinc finger C-x8-C-x5-C-x3-H type (and simila	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
LPAL13_320045300 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_180780.1 ↔ LdBPK_323840.1 OG7 LdBPK_180780.1 ↔ LdBPK_323840.1	Both
LPAL13_210015300 ⚠ Core histone H2A/H2B/H3/H4, putative	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
LPAL13_150006400 ⚠ zinc finger (CCCH type) protein, putative	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
LPAL13_340015200 ⚠ Zinc finger C-x8-C-x5-C-x3-H type (and simila	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
LPAL13_150006600 ⚠ zinc finger (CCCH type) protein, putative	—	OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	OG7
LPAL13_090016200 ⚠ DNA-directed RNA polymerase III subunit, puta	—	OG7 Tb927.10.13320 ↔ Tb927.11.14490	OG7
LPAL13_190012200 ⚠ DNA-directed RNA polymerase III subunit C11,	—	OG7 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13310 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.10420	OG7
LPAL13_210015500 ⚠ Core histone H2A/H2B/H3/H4, putative	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
LPAL13_290021900 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
LPAL13_290022000 ⚠ histone H2A	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
LPAL13_210015400 ⚠ Core histone H2A/H2B/H3/H4, putative	—	OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	OG7
LPAL13_190014800 ⚠ histone H3 variant, putative	—	OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	OG7
LPAL13_170007700 ⚠ histone H2A, putative	—	OG6 Tb927.10.13320 ↔ Tb927.7.6360 OG7 Tb927.10.13310 ↔ Tb927.7.6360 OG7 Tb927.10.13320 ↔ Tb927.7.6360	Both
LPAL13_320045400 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_180780.1 ↔ LdBPK_323840.1 OG7 LdBPK_180780.1 ↔ LdBPK_323840.1	Both
LPAL13_320014000 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_180780.1 ↔ LdBPK_320890.1 OG7 LdBPK_180780.1 ↔ LdBPK_320890.1	Both
LPAL13_300040200 ⚠ Zinc finger CCCH domain-containing protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_303630.1 OG7 LdBPK_180780.1 ↔ LdBPK_303630.1	Both
LPAL13_270033200 ⚠ WD-repeat protein	—	OG6 LdBPK_180780.1 ↔ LdBPK_272430.1 OG7 LdBPK_180780.1 ↔ LdBPK_272430.1	Both
LPAL13_030011200 ⚠ Aminoacyl-tRNA editing domain containing prot	—	OG6 LdBPK_030690.1 ↔ LdBPK_180780.1 OG7 LdBPK_030690.1 ↔ LdBPK_180780.1	Both
LPAL13_270020900 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_005513 ↔ TCSYLVIO_006204 OG7 TCSYLVIO_005513 ↔ TCSYLVIO_006204	Both
LPAL13_140009000 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_140390.1 ↔ LdBPK_180780.1 OG7 LdBPK_140390.1 ↔ LdBPK_180780.1	Both
LPAL13_180010800 ⚠ DNA-directed RNA polymerase I subunit RPB5z,	—	OG6 Tb927.10.13310 ↔ Tb927.10.13320 OG7 Tb927.10.13310 ↔ Tb927.10.13320	Both
LPAL13_050011600 phophatase-like protein	—	OG6 LdBPK_050720.1 ↔ LdBPK_180780.1	OG6
LPAL13_200048300 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG6 Tb927.10.13320 ↔ Tb927.4.3810 OG7 Tb927.10.13320 ↔ Tb927.11.630 OG7 Tb927.10.13320 ↔ Tb927.4.3810	Both
LPAL13_280013800 ⚠ RNA polymerase B subunit RPB8, putative	—	OG6 Tb927.10.13320 ↔ Tb927.11.7930 OG7 Tb927.10.13320 ↔ Tb927.11.7930	Both
LPAL13_310031800 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13310 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.8.5090	Both
LPAL13_320019100 ⚠ RNA polymerase-like protein, putative	—	OG6 Tb927.10.13320 ↔ Tb927.11.14490 OG7 Tb927.10.13320 ↔ Tb927.11.14490	Both
LPAL13_200007500 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13310 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.8.5090	Both
LPAL13_190015100 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG6 Tb927.10.13320 ↔ Tb927.10.15370 OG7 Tb927.10.13310 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.3.5500	Both
LPAL13_280006400 ⚠ DNA-direcetd RNA polymerase II, subunit 9, pu	—	OG6 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13320 ↔ Tb927.11.7280 OG7 Tb927.10.13310 ↔ Tb927.11.10420 OG7 Tb927.10.13320 ↔ Tb927.11.10420	Both
LPAL13_290009100 ⚠ RNA polymerase Rpb4, putative	—	OG6 Tb927.10.13320 ↔ Tb927.3.5270 OG7 Tb927.10.13320 ↔ Tb927.3.5270	Both
LPAL13_290006400 ⚠ DNA-directed RNA polymerase I-like protein	—	OG6 Tb927.10.13320 ↔ Tb927.3.5500 OG7 Tb927.10.13310 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.10.15370 OG7 Tb927.10.13320 ↔ Tb927.3.5500	Both
LPAL13_100015500 ⚠ histone H3, putative	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both
LPAL13_100014400 ⚠ histone H3, putative	—	OG6 Tb927.10.13320 ↔ Tb927.10.15350 OG7 Tb927.10.13310 ↔ Tb927.10.15350 OG7 Tb927.10.13320 ↔ Tb927.10.15350	Both
LPAL13_160018400 ⚠ DNA-directed rna polymerase I largest subunit	—	OG6 Tb927.10.13320 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.4.5020 OG7 Tb927.10.13310 ↔ Tb927.8.5090 OG7 Tb927.10.13320 ↔ Tb927.8.5090	Both