LPAL13_350070200

OTU-like cysteine protease, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102949 OG7: OG7_0008044 18 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 18 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_320024800
rab11B GTPase, putative
— OG6
LPAL13_170018100 ⚠
MSP (Major sperm protein) domain containing p
— OG7
LPAL13_350070700 ⚠
disgorgin, putative
— OG7
LPAL13_350070800 ⚠
rab-like GTPase activating protein, putative
— Both
LPAL13_350073200
homocysteine S-methyltransferase, putative
— Both
LPAL13_310007600 ⚠
hypothetical protein
— Both
LPAL13_350071900 ⚠
Sucrase/ferredoxin-like, putative
— Both
LPAL13_340045100
calmodulin-like protein
— OG6
LPAL13_320035500
hypothetical protein, conserved
— Both
LPAL13_090010000 ⚠
serine/threonine protein phosphatase, putativ
— OG6
LPAL13_080011100
hypothetical protein, conserved
— Both
LPAL13_090016100 ⚠
MSP (Major sperm protein) domain containing p
— Both
LPAL13_340034900
trypanothione-dependent glyoxalase I
— Both
LPAL13_340059100
hypothetical protein, conserved
— Both
LPAL13_200017300
Uncharacterised ACR, YggU family COG1872, put
— Both
LPAL13_200036700
D-Tyr-tRNA(Tyr) deacylase, putative
— Both
LPAL13_340014900
hypothetical protein, conserved
— Both
LPAL13_050006000 ⚠
phosphoprotein phosphatase, putative
— OG6
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.