LTRL590_090013800

DEAD/DEAH box helicase-like protein

Leishmania tropica L590 OG6: OG6_158005 OG7: OG7_0052329 54 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Query Computational only Exp + computational Experimental only

Interactions 54 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_220019000 hypothetical protein, conserved	—	OG6 Tb927.11.12930 ↔ Tb927.7.3460 OG6 TCSYLVIO_001807 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_001807 ↔ TCSYLVIO_006554 OG7 Tb927.11.12930 ↔ Tb927.7.3460	Both
LTRL590_270016100 hypothetical protein, conserved	—	OG6 Tb927.11.12930 ↔ Tb927.11.1630 OG6 TCSYLVIO_005482 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_005482 ↔ TCSYLVIO_006554 OG7 Tb927.11.12930 ↔ Tb927.11.1630	Both
LTRL590_130006300 hypothetical protein, conserved	—	OG6 Tb927.11.12930 ↔ Tb927.11.4650 OG6 TCSYLVIO_002175 ↔ TCSYLVIO_006554 OG7 Tb927.11.12930 ↔ Tb927.11.4650 OG7 TCSYLVIO_002175 ↔ TCSYLVIO_006554	Both
LTRL590_170012700 hypothetical protein, conserved	—	OG6 Tb927.11.12930 ↔ Tb927.5.2070 OG6 TCSYLVIO_006554 ↔ TCSYLVIO_009032 OG7 Tb927.11.12930 ↔ Tb927.5.2070 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_009032	Both
LTRL590_360038300 hypothetical protein, conserved	—	OG6 Tb927.10.7380 ↔ Tb927.11.12930 OG6 TCSYLVIO_005046 ↔ TCSYLVIO_006554 OG7 Tb927.10.7380 ↔ Tb927.11.12930 OG7 TCSYLVIO_005046 ↔ TCSYLVIO_006554	Both
LTRL590_260007300 ras-like small GTPases, putative	—	OG6 Tb927.11.12930 ↔ Tb927.7.1640 OG6 TCSYLVIO_002378 ↔ TCSYLVIO_006554 OG7 Tb927.11.12930 ↔ Tb927.7.1640 OG7 TCSYLVIO_002378 ↔ TCSYLVIO_006554	Both
LTRL590_110020900 tRNA pseudouridine synthase D (TruD), putativ	—	OG6 Tb927.11.12930 ↔ Tb927.11.5990 OG6 TCSYLVIO_001604 ↔ TCSYLVIO_006554 OG7 Tb927.11.12930 ↔ Tb927.11.5990 OG7 TCSYLVIO_001604 ↔ TCSYLVIO_006554	Both
LTRL590_060010200 ⚠ SpoU rRNA Methylase family, putative	—	OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007498	OG7
LTRL590_350015300 ⚠ Zinc finger C-x8-C-x5-C-x3-H type (and simila	—	OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	OG7
LTRL590_330009900 hypothetical protein, conserved	—	OG6 TCSYLVIO_004844 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_004844 ↔ TCSYLVIO_006554	Both
LTRL590_290005300 ribosomal protein L3-like protein	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_010727 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_010727	Both
LTRL590_210025300 mitochondrial RNA binding complex 1 subunit,	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_009360 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_009360	Both
LTRL590_160006800 50S ribosomal protein L17, putative	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007654 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007654	Both
LTRL590_270010100 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007675 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007675	Both
LTRL590_270010000 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007675 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007675	Both
LTRL590_080011100 hypothetical protein, conserved	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_010573 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_010573	Both
LTRL590_270009900 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007675 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007675	Both
LTRL590_040007500 Mitochondrial 39-S ribosomal protein L47 (MRP	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007130 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007130	Both
LTRL590_080007600 Ribosomal protein L9, N-terminal domain conta	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_010544 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_010544	Both
LTRL590_040006100 hypothetical protein, conserved	—	OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007121	OG7
LTRL590_320034200 ⚠ SpoU rRNA Methylase family, putative	—	OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007498	OG7
LTRL590_190009200 hypothetical protein, conserved	—	OG7 TCSYLVIO_006046 ↔ TCSYLVIO_006554	OG7
LTRL590_010007700 pseudouridylate synthase-like protein	—	OG6 TCSYLVIO_003456 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003456 ↔ TCSYLVIO_006554	Both
LTRL590_150006500 ⚠ zinc finger (CCCH type) protein, putative	—	OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	OG7
LTRL590_350015500 ⚠ Zinc finger C-x8-C-x5-C-x3-H type (and simila	—	OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	OG7
LTRL590_150006300 ⚠ zinc finger (CCCH type) protein, putative	—	OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	OG7
LTRL590_270006400 ⚠ WW domain/Zinc finger C-x8-C-x5-C-x3-H type (	—	OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	OG7
LTRL590_260018500 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 TCSYLVIO_005645 ↔ TCSYLVIO_006554	OG7
LTRL590_050006900 ⚠ 50S ribosome-binding GTPase, putative	—	OG7 TCSYLVIO_005645 ↔ TCSYLVIO_006554	OG7
LTRL590_050009100 ⚠ GTPase, putative	—	OG7 TCSYLVIO_005645 ↔ TCSYLVIO_006554	OG7
LTRL590_330032400 ⚠ ras-like small GTPases, putative	—	OG7 TCSYLVIO_005645 ↔ TCSYLVIO_006554	OG7
LTRL590_300032900 hypothetical protein, conserved	—	OG6 TCSYLVIO_003296 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003296 ↔ TCSYLVIO_006554	Both
LTRL590_300016500 DNAj-like protein	—	OG6 TCSYLVIO_003164 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003164 ↔ TCSYLVIO_006554	Both
LTRL590_350034700 SpoU rRNA Methylase family, putative	—	OG6 Tb927.11.12930 ↔ Tb927.9.12850 OG7 Tb927.11.12930 ↔ Tb927.9.12850	Both
LTRL590_300034400 hypothetical protein, conserved	—	OG6 Tb927.11.12930 ↔ Tb927.6.4080 OG7 Tb927.11.12930 ↔ Tb927.6.4080	Both
LTRL590_320024600 Phosphatidylethanolamine-binding protein, put	—	OG6 Tb927.11.12930 ↔ Tb927.11.14980 OG7 Tb927.11.12930 ↔ Tb927.11.14980	Both
LTRL590_340042300 50S ribosomal protein L13-like protein	—	OG6 Tb927.11.12930 ↔ Tb927.4.1070 OG7 Tb927.11.12930 ↔ Tb927.4.1070	Both
LTRL590_300042400 ⚠ Zinc finger CCCH domain-containing protein	—	OG6 TCSYLVIO_003384 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003384 ↔ TCSYLVIO_006554	Both
LTRL590_350059100 ⚠ GTP-binding protein, putative	—	OG6 TCSYLVIO_005645 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_005645 ↔ TCSYLVIO_006554	Both
LTRL590_290028200 ⚠ conserved hypothetical protein, putative	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_006554	Both
LTRL590_300015500 ⚠ conserved hypothetical protein, putative	—	OG6 TCSYLVIO_003157 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_003157 ↔ TCSYLVIO_006554	Both
LTRL590_250024500 hypothetical protein, conserved	—	OG6 TCSYLVIO_006359 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_006359 ↔ TCSYLVIO_006554	Both
LTRL590_310024400 hypothetical protein, conserved	—	OG6 TCSYLVIO_002910 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_002910 ↔ TCSYLVIO_006554	Both
LTRL590_270010200 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_006554 ↔ TCSYLVIO_007675 OG7 TCSYLVIO_006554 ↔ TCSYLVIO_007675	Both
LTRL590_280031100 hypothetical protein, conserved	—	OG6 Tb927.11.11630 ↔ Tb927.11.12930 OG7 Tb927.11.11630 ↔ Tb927.11.12930	Both
LTRL590_340018900 RNA editing associated helicase 2, putative	—	OG6 TCSYLVIO_003932 ↔ TCSYLVIO_006554	OG6
LTRL590_160005100 hypothetical protein, conserved	—	OG6 TCSYLVIO_001227 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_001227 ↔ TCSYLVIO_006554	Both
LTRL590_230021500 hypothetical protein, conserved	—	OG6 TCSYLVIO_000178 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_000178 ↔ TCSYLVIO_006554	Both
LTRL590_350045000 ⚠ 30S Ribosomal protein S17-like protein	—	OG6 TCSYLVIO_005773 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_005773 ↔ TCSYLVIO_006554	Both
LTRL590_000007800 ⚠ 40S ribosomal protein S11, putative	—	OG6 TCSYLVIO_005773 ↔ TCSYLVIO_006554 OG7 TCSYLVIO_005773 ↔ TCSYLVIO_006554	Both

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