LbrM.18.1730

P-type H+-ATPase, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100641 OG7: OG7_0001065 45 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 45 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.06.0010 ⚠ ABC transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
LbrM.34.0080 ⚠ phosphatidylinositol-specific phospholipase-l	—	OG6 Tb927.10.12500 ↔ Tb927.11.5970 OG6 Tb927.10.12510 ↔ Tb927.11.5970 OG7 Tb927.10.12500 ↔ Tb927.11.5970 OG7 Tb927.10.12510 ↔ Tb927.11.5970	Both
LbrM.35.6490 ⚠ glucose transporter 2	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
LbrM.11.1090 ⚠ Nodulin-like/Major Facilitator Superfamily, p	—	OG6 Tb927.10.12500 ↔ Tb927.11.6040 OG6 Tb927.10.12510 ↔ Tb927.11.6040	OG6
LbrM.31.1520 ⚠ multidrug resistance protein, copy 1-like pro	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.35.3110 ⚠ ATP-binding cassette protein, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
LbrM.18.1740 ⚠ P-type H+-ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.12510 OG7 Tb927.10.12500 ↔ Tb927.10.12510	Both
LbrM.18.1550 ⚠ P-type H+-ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.12510 OG7 Tb927.10.12500 ↔ Tb927.10.12510	Both
LbrM.10.0400 ⚠ folate/biopterin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.10.0020 ⚠ pteridin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.31.1510 ⚠ p-glycoprotein e, putative	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.23.0280 ⚠ ABC-thiol transporter	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.10.0390 ⚠ folate/biopterin transporter, putative (fragm	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.10.0370 ⚠ folate/biopterin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.33.0290 ⚠ glucose transporter/membrane transporter D2,	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
LbrM.31.1500 ⚠ p-glycoprotein e	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.19.0900 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
LbrM.19.1940 ⚠ hypothetical protein, conserved (fragment)	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
LbrM.12.0660 ⚠ ser/thr protein phosphatase, putative	—	OG6 Tb927.1.4050 ↔ Tb927.10.12510 OG6 Tb927.1.4050 ↔ Tb927.10.12500	OG6
LbrM.06.1250 ⚠ pteridine transporter, putative	—	OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	OG7
LbrM.20.0600 ⚠ ABC transporter-like protein	—	OG7 Tb927.10.12500 ↔ Tb927.4.4490 OG7 Tb927.10.12510 ↔ Tb927.4.4490 OG7 Tb927.10.12500 ↔ Tb927.8.2160 OG7 Tb927.10.12510 ↔ Tb927.8.2160	OG7
LbrM.32.3960 ⚠ BT1 family, putative	—	OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	OG7
LbrM.24.0690 ⚠ myo-inositol/proton symporter (MIT)	—	OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	OG7
LbrM.23.0230 ⚠ multidrug resistance protein, putative, ABC t	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.31.2040 ⚠ amino acid permease	—	OG6 LdBPK_181510.1 ↔ LdBPK_311850.1	OG6
LbrM.31.2060 ⚠ amino acid permease	—	OG6 LdBPK_181510.1 ↔ LdBPK_311850.1	OG6
LbrM.31.2000 ⚠ amino acid permease	—	OG6 LdBPK_181510.1 ↔ LdBPK_311850.1	OG6
LbrM.31.1990 ⚠ amino acid permease	—	OG6 LdBPK_181510.1 ↔ LdBPK_311850.1	OG6
LbrM.34.5090 ⚠ biopterin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080	OG6
LbrM.31.1340 ⚠ monoglyceride lipase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.4.4360 OG6 Tb927.10.12510 ↔ Tb927.4.4360 OG7 Tb927.10.12500 ↔ Tb927.4.4360 OG7 Tb927.10.12510 ↔ Tb927.4.4360	Both
LbrM.26.2600 ⚠ p-glycoprotein-like protein, multidrug resist	—	OG6 Tb927.10.12500 ↔ Tb927.11.540 OG6 Tb927.10.12510 ↔ Tb927.11.540 OG7 Tb927.10.12500 ↔ Tb927.11.540 OG7 Tb927.10.12510 ↔ Tb927.11.540	Both
LbrM.25.0480 ⚠ ABC transporter, mitochondrial, putative	—	OG6 Tb927.10.12500 ↔ Tb927.11.540 OG6 Tb927.10.12510 ↔ Tb927.11.540 OG7 Tb927.10.12500 ↔ Tb927.11.540 OG7 Tb927.10.12510 ↔ Tb927.11.540	Both
LbrM.35.6480 ⚠ glucose transporter 3, putative (fragment)	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
LbrM.34.1990 ⚠ calcium motive p-type ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.15460 OG6 Tb927.10.12510 ↔ Tb927.9.15460 OG7 Tb927.10.12500 ↔ Tb927.9.15460 OG7 Tb927.10.12510 ↔ Tb927.9.15460	Both
LbrM.31.2020 ⚠ amino acid permease	—	OG6 LdBPK_181510.1 ↔ LdBPK_311850.1	OG6
LbrM.22.1590 ⚠ phosphoinositide-specific phospholipase C, pu	—	OG6 Tb927.10.12500 ↔ Tb927.11.5970 OG6 Tb927.10.12510 ↔ Tb927.11.5970 OG7 Tb927.10.12500 ↔ Tb927.11.5970 OG7 Tb927.10.12510 ↔ Tb927.11.5970	Both
LbrM.10.0410 ⚠ folate/biopterin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.10.1460 ⚠ pteridine transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.35.6600 ⚠ glucose transporter 1	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
LbrM.06.0080 ⚠ ATP-binding cassette protein subfamily G, mem	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
LbrM.23.0420 ⚠ ATP-binding cassette protein subfamily G, mem	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
LbrM.10.0380 ⚠ folate/biopterin transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
LbrM.31.1650 ⚠ pentamidine resistance protein 1	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.23.0740 ⚠ p-glycoprotein, putative, ABC transporter, pu	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
LbrM.15.0930 ⚠ ABC transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both