LbrM.20.2060

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain/Domain of unknown function (DUF1981), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_154458 OG7: OG7_0001170 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.2520 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0750 ⚠
elongation factor 1-beta
— OG7
LbrM.34.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2160 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LbrM.26.1870 ⚠
microtubule-associated protein, putative
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.31.0130 ⚠
hypothetical protein, unknown function
— OG7
LbrM.18.0520 ⚠
tubulin-specific chaperone, putative
— OG7
LbrM.12.0530 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.0740 ⚠
pdz domain containing protein, putative
— OG7
LbrM.16.1610 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0840 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.0410 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7360 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.34.2590 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3290 ⚠
fibrillarin
— OG7
LbrM.21.1760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LbrM.24.2040 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.34.2330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.27.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1120 ⚠
intraflagellar transport protein 122, putativ
— OG7
LbrM.33.2040 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1660 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.12.0140 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0020 ⚠
translation initiation factor EIF-2b alpha su
— OG7
LbrM.32.0380 ⚠
intraflagellar transport protein 140, putativ
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.21.0890 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.27.1310 ⚠
translation initiation factor eIF2B delta sub
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7340 ⚠
elks delta-like protein, hypothetical protein
— OG7
LbrM.33.1850 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0710 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0940 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0580 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LbrM.14.1130 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1070 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LbrM.20.0840 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0110 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2910 ⚠
dynein intermediate chain, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.