LbrM.35.3140

PHF5-like protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102593 OG7: OG7_0008087 10 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 10 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.29.0330 ⚠
RNA binding protein, putative
— Both
LbrM.28.2790
splicing factor 3B subunit 1, putative
— Both
LbrM.05.0860 ⚠
CPSF A subunit region, putative
— Both
LbrM.35.3260
pre-mRNA branch site protein p14, putative
— Both
LbrM.30.0650
spliceosome-associated protein, putative
— Both
LbrM.34.4080
Splicing factor 3B subunit 10 (SF3b10), putat
— Both
LbrM.25.0080 ⚠
poly(A)-binding protein 3, putative
— OG7
LbrM.30.3750 ⚠
CPSF-domain protein, putative
— OG7
LbrM.34.4130 ⚠
polyadenylate-binding protein 2
— OG7
LbrM.34.4980 ⚠
polyadenylate-binding protein 1, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.