LmjF.21.1750

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_147322 OG7: OG7_0027186 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.25.2030 ⚠
mitochondrial import inner membrane transloca
— OG7
LmjF.08.1050 ⚠
cathepsin L-like protease
— OG7
LmjF.08.1080 ⚠
cathepsin L-like protease
— OG7
LmjF.08.1030 ⚠
cathepsin L-like protease
— OG7
LmjF.08.1060 ⚠
cathepsin L-like protease
— OG7
LmjF.08.1040 ⚠
cathepsin L-like protease
— OG7
LmjF.19.1420 ⚠
cysteine peptidase A (CPA)
— OG7
LmjF.08.1020 ⚠
cathepsin L-like protease
— OG7
LmjF.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.32.0100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.36.6780 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LmjF.26.0160 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LmjF.08.1070 ⚠
cathepsin L-like protease
— OG7
LmjF.35.3520 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.29.2400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.33.0780 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.24.0110 ⚠
poly A polymerase regulatory subunit, putativ
— OG7
LmjF.35.2620 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.31.0910 ⚠
hypothetical protein, unknown function
— OG7
LmjF.31.0920 ⚠
sodium stibogluconate resistance protein, put
— OG7
LmjF.31.0960 ⚠
sodium stibogluconate resistance protein, put
— OG7
LmjF.31.0930 ⚠
sodium stibogluconate resistance protein, put
— OG7
LmjF.31.0950 ⚠
sodium stibogluconate resistance protein, put
— OG7
LmjF.09.0300
hypothetical protein, conserved
— Both
LmjF.26.1030
hypothetical protein, conserved
— Both
LmjF.35.3380 ⚠
poly A polymerase regulatory subunit, putativ
— Both
LmjF.26.2280
nitrilase, putative
— Both
LmjF.29.0820 ⚠
CPC cysteine peptidase, Clan CA, family C1, C
— Both
LmjF.33.0295
autophagocytosis protein, putative
— Both
LmjF.33.0700
hypothetical protein, conserved
— Both
LmjF.25.1450
Peptide chain release factor 1, mitochondrial
— Both
LmjF.17.1160
UDP-sugar pyrophosphorylase
— Both
LmjF.05.0270
hypothetical protein, conserved
— Both
LmjF.03.0770
Ubiquitin-like domain containing protein, put
— Both
LmjF.35.0190 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LmjF.34.1280
hypothetical protein, conserved
— Both
LmjF.20.0660
serine/threonine protein phosphatase 2A regul
— Both
LmjF.28.2220
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.18.0090 ⚠
alpha glucosidase II subunit, putative
— Both
LmjF.33.0220
hypothetical protein, conserved
— Both
LmjF.22.1250
hypothetical protein, conserved
— Both
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.30.3110
S-adenosylmethionine decarboxylase
— Both
LmjF.28.1580
phosphonopyruvate decarboxylase-like protein
— Both
LmjF.23.1470
hypothetical protein, conserved
— Both
LmjF.08.1010 ⚠
cysteine peptidase B (CPB)
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.