LmxM.22.0520

Rab-GTPase-TBC domain containing protein, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101355 OG7: OG7_0003032 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmxM.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmxM.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmxM.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmxM.10.0140 ⚠
DEAD/DEAH box helicase, putative, mitochondri
— OG7
LmxM.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmxM.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmxM.31.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmxM.20.1550 ⚠
amidohydrolase, putative
— Both
LmxM.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmxM.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmxM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmxM.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmxM.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmxM.34.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmxM.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmxM.32.2260
glycosyl hydrolase-like protein
— Both
LmxM.09.0940
hypothetical protein, conserved
— Both
LmxM.32.1910
ribosome assembly protein RRB1, putative
— Both
LmxM.26.1290
Cupin-like domain containing protein, putativ
— Both
LmxM.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
LmxM.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmxM.26.1220 ⚠
hypothetical protein, conserved
— Both
LmxM.34.1990
U3 small nucleolar RNA-associated protein 6,
— Both
LmxM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— Both
LmxM.10.0310 ⚠
protein transport protein SEC23, putative
— Both
LmxM.34.4550
hypothetical protein, conserved
— Both
LmxM.32.2980
hypothetical protein, conserved
— Both
LmxM.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmxM.20.0705
conserved protein, unknown function
— Both
LmxM.30.1130 ⚠
amidohydrolase, putative
— Both
LmxM.20.1560 ⚠
amidohydrolase, putative
— Both
LmxM.29.1380 ⚠
amidohydrolase, putative
— Both
LmxM.20.1570 ⚠
amidohydrolase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.