LmxM.25.2340

AGC essential kinase 1
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_105018 OG7: OG7_0000103 15 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 15 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.22.0530
peptidyl-prolyl cis-trans isomerase, putative
— OG6
LmxM.17.0580
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG6
LmxM.06.1070
deoxyribose-phosphate aldolase, putative
— OG6
LmxM.15.0520
ecotin, putative
— OG6
LmxM.04.0580
spermidine synthase, putative
— OG6
LmxM.01.0830 ⚠
hypothetical protein
— OG6
LmxM.02.0740 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG6
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG6
LmxM.21.1552
ATP-dependent RNA helicase SUB2, putative
— OG6
LmxM.07.0190
phosphotyrosyl phosphate activator protein, p
— OG6
LmxM.19.0160
metallo-peptidase, Clan MG, Family M24
— OG6
LmxM.32.2520
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG6
LmxM.33.0160 ⚠
malate dehydrogenase, putative
— OG6
LmxM.36.6570
y113g7b.23 protein-like protein, hypothetical
— OG6
LmxM.33.0140 ⚠
malate dehydrogenase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.