LmxM.27.0880

2-oxoglutarate dehydrogenase subunit, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100311 OG7: OG7_0003220 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.36.5120 ⚠
40S ribosomal protein SA, putative
— Both
LmxM.33.0860 ⚠
60S ribosomal protein L13a, putative
— Both
LmxM.13.1230 ⚠
40S ribosomal protein S4, putative
— Both
LmxM.13.1220 ⚠
40S ribosomal protein S4, putative
— Both
LmxM.29.3040 ⚠
eukaryotic translation initiation factor 3 su
— Both
LmxM.36.0940 ⚠
40S ribosomal protein S18, putative
— Both
LmxM.15.0950 ⚠
40S ribosomal protein S3, putative
— Both
LmxM.36.0930 ⚠
40S ribosomal protein S18, putative
— Both
LmxM.32.0920 ⚠
40S ribosomal protein S3, putative
— Both
LmxM.34.5100 ⚠
60S ribosomal protein L37
— Both
LmxM.32.1955 ⚠
60S ribosomal protein L37
— Both
LmxM.30.0390 ⚠
Calpain-like protein 2
— OG6
LmxM.21.0430 ⚠
hypothetical protein, conserved
— Both
LmxM.22.1560 ⚠
40S ribosomal protein L14, putative
— Both
LmxM.22.1520 ⚠
40S ribosomal protein L14, putative
— Both
LmxM.36.5010 ⚠
40S ribosomal protein SA, putative
— Both
LmxM.15.0200 ⚠
60S ribosomal protein L13a, putative
— Both
LmxM.36.1925 ⚠
60S ribosomal protein L37a
— Both
LmxM.21.1820 ⚠
60S ribosomal protein L37a, putative
— Both
LmxM.26.1710 ⚠
cytochrome c oxidase subunit V, putative
— Both
LmxM.36.3470 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
LmxM.25.1710 ⚠
pyruvate dehydrogenase E1 beta subunit, putat
— Both
LmxM.27.2480 ⚠
hypothetical protein, conserved, WD-repeat pr
— Both
LmxM.36.2660 ⚠
dihydrolipoamide acetyltransferase precursor,
— OG7
LmxM.10.0140 ⚠
DEAD/DEAH box helicase, putative, mitochondri
— OG7
LmxM.31.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmxM.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmxM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmxM.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmxM.19.0300 ⚠
RNA binding protein, putative
— OG7
LmxM.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmxM.18.0230 ⚠
60S ribosomal protein L7, putative
— OG7
LmxM.18.0620 ⚠
60S ribosomal protein L10a, putative
— Both
LmxM.27.0510 ⚠
cysteine peptidase, Clan CA, family C2, putat
— Both
LmxM.27.0490 ⚠
calpain-like cysteine peptidase, putative
— Both
LmxM.08_29.0110 ⚠
C2 domain in Dock180 and Zizimin proteins, pu
— Both
LmxM.26.0180 ⚠
60S ribosomal protein L7, putative
— Both
LmxM.26.0170 ⚠
60S ribosomal protein L7, putative
— Both
LmxM.27.2500 ⚠
hypothetical protein, conserved
— Both
LmxM.33.2780 ⚠
40S ribosomal protein S19 protein, putative
— Both
LmxM.08_29.2860 ⚠
40S ribosomal protein S19-like protein
— Both
LmxM.08_29.1460 ⚠
hypothetical protein, conserved
— Both
LmxM.22.0990 ⚠
hypothetical protein, conserved
— Both
LmxM.33.2700 ⚠
eukaryotic translation initiation factor 3 su
— OG6
LmxM.29.0570 ⚠
spliceosome-associated protein, putative
— Both
LmxM.34.3100 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.07.0870 ⚠
splicing factor ptsr1-like protein
— Both
LmxM.36.1340 ⚠
N-acetyltransferase subunit Nat1, putative
— Both
LmxM.15.0440 ⚠
tb-292 membrane associated protein-like prote
— OG6
LmxM.17.1290 ⚠
eukaryotic translation initiation factor 3 su
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.