LmxM.36.0120

cap guanine-N7 methyltransferase
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_137199 OG7: OG7_0006447 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.07.0831 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmxM.20.0210 ⚠
kelch domain-containing protein
— OG7
LmxM.29.1930 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— OG7
LmxM.32.2340 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— OG7
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmxM.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmxM.26.0900 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LmxM.34.4710 ⚠
Hsp70 protein, putative
— OG7
LmxM.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmxM.07.0840 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.0460 ⚠
hypothetical protein, unknown function
— OG7
LmxM.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmxM.01.0640 ⚠
HSP70-like protein
— OG7
LmxM.07.0830 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.1370 ⚠
heat shock protein, putative
— OG7
LmxM.05.0260 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LmxM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LmxM.13.0880 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.0910 ⚠
glutathione synthetase, putative
— OG7
LmxM.13.1400 ⚠
hypothetical protein, conserved
— OG7
LmxM.01.0380 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— OG7
LmxM.17.0980 ⚠
Mak10 subunit, NatC N(alpha)-terminal acetylt
— OG7
LmxM.29.2490 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.07.0720 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.1400 ⚠
LYAR-type C2HC zinc finger, putative
— OG7
LmxM.24.2240 ⚠
ATP:cob(I)alamin adenosyltransferase, putativ
— OG7
LmxM.29.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmxM.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmxM.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmxM.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LmxM.29.2550 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.34.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmxM.08_29.1270 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmxM.02.0710 ⚠
serine peptidase, putative, ATP-dependent Clp
— OG7
LmxM.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmxM.31.2150 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0410 ⚠
translation initiation factor SUI1, putative
— OG7
LmxM.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmxM.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.2460 ⚠
heat shock 70-related protein 1, mitochondria
— OG7
LmxM.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1940 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— OG7
LmxM.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmxM.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.