LpyrH10_01_1590

exosome complex exonuclease RRP45 homolog, putative

Leptomonas pyrrhocoris H10 OG6: OG6_100420 OG7: OG7_0002825 76 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 76 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_17_0010 ⚠ exosome complex exonuclease, putative,ribosom	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 +4 more	Both
LpyrH10_27_0650 ⚠ ribosomal RNA processing protein, putative	—	OG6 LdBPK_020290.1 ↔ LdBPK_221430.1 OG6 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 +2 more	Both
LpyrH10_40_0160 ⚠ exosome complex exonuclease RRP40, putative	—	OG6 LdBPK_040130.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.9.7070 OG6 Tb927.11.16600 ↔ Tb927.9.7070 OG7 Tb927.6.670 ↔ Tb927.9.7070 +2 more	Both
LpyrH10_06_2700 ⚠ exosome-associated protein 4, putative	—	OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 LdBPK_020290.1 ↔ LdBPK_221430.1	OG7
LpyrH10_06_0550 ⚠ exosome complex exonuclease rrp41, putative	—	OG6 Tb927.10.7450 ↔ Tb927.6.670 OG6 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 +2 more	Both
LpyrH10_05_3290 ⚠ exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
LpyrH10_02_8070 ⚠ Proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
LpyrH10_02_4740 ⚠ heat-shock protein hsp70, putative, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_03_1730 ⚠ Csl4p homologue, putative	—	OG6 Tb927.11.16600 ↔ Tb927.5.1200 OG6 Tb927.5.1200 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.5.1200 OG7 Tb927.5.1200 ↔ Tb927.6.670	Both
LpyrH10_02_6730 ⚠ glucose-regulated protein 78, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_01_9200 ⚠ heat shock protein 70-related protein	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_02_4760 ⚠ heat-shock protein hsp70, putative, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_02_4730 ⚠ heat-shock protein hsp70, putative, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_02_4750 ⚠ heat-shock protein hsp70, putative, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LpyrH10_02_3980 ⚠ exosome-associated protein 2, putative	—	OG6 Tb927.11.16600 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.6.670	Both
LpyrH10_02_1200 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LpyrH10_18_0280 ⚠ Proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LpyrH10_09_1680 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LpyrH10_05_1190 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LpyrH10_05_1170 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LpyrH10_01_4350 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001893	OG6
LpyrH10_04_3930 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003184 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003184	Both
LpyrH10_01_6200 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LpyrH10_35_0530 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LpyrH10_06_5180 ⚠ Chaperonin, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LpyrH10_20_0060 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LpyrH10_09_1870 ⚠ Proteasome alpha 1 subunit, putative, putativ	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LpyrH10_07_1540 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LpyrH10_14_2360 ⚠ 20S proteasome subunit alpha 5, (putative)	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LpyrH10_28_0640 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	OG7
LpyrH10_17_0330 ⚠ proteasome alpha 3 subunit, putative, putativ	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LpyrH10_02_4690 ⚠ heat shock protein 70, putative, putative mit	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710	OG6
LpyrH10_04_0670 ⚠ Dna-directed RNA polymerase, alpha subunit, p	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	OG7
LpyrH10_06_0510 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	OG7
LpyrH10_25_1970 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LpyrH10_01_7130 ⚠ hypothetical protein, conserved, putative mit	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LpyrH10_32_0970 ⚠ DNA-directed RNA polymerase II subunit 2, put	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LpyrH10_01_8350 ⚠ hypothetical protein, conserved	—	OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	OG7
LpyrH10_01_8850 ⚠ heat shock 70 protein-like protein, putative	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LpyrH10_33_0580 ⚠ HSP70-like protein, putative mitochondrial	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LpyrH10_06_3270 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LpyrH10_05_1640 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003934 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003934	Both
LpyrH10_16_2110 ⚠ paraflagellar rod component, putative, putati	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006797	Both
LpyrH10_01_7250 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LpyrH10_11_1630 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009798	Both
LpyrH10_14_2210 ⚠ Proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LpyrH10_33_0490 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003433 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003433	Both
LpyrH10_28_1090 ⚠ adaptor complex protein (AP) 3 delta subunit	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010530	Both
LpyrH10_36_0020 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	Both
LpyrH10_08_1760 ⚠ hypothetical protein, conserved, putative mit	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004312	Both

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