LpyrH10_04_3570

ubiquitin-protein ligase, putative

Leptomonas pyrrhocoris H10 OG6: OG6_100865 OG7: OG7_0000785 369 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 369 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_01_9250 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_01_5840 ⚠ Hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_17_1440 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_04_1730 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_01_9070 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070440.1 ↔ LdBPK_211260.1 OG7 LdBPK_070440.1 ↔ LdBPK_261100.1 OG7 TCSYLVIO_001495 ↔ TCSYLVIO_009791	OG7
LpyrH10_01_6640 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_13_0840 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	Both
LpyrH10_18_1130 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_001642 ↔ TCSYLVIO_003155 OG6 LdBPK_110890.1 ↔ LdBPK_300970.1 OG7 LdBPK_110890.1 ↔ LdBPK_300970.1 OG7 TCSYLVIO_001642 ↔ TCSYLVIO_003155	Both
LpyrH10_01_7930 ⚠ unspecified product	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_19_0450 ⚠ 33 kDa inner dynein arm light chain, axonemal	—	OG7 LdBPK_070440.1 ↔ LdBPK_211260.1 OG7 LdBPK_070440.1 ↔ LdBPK_261100.1 OG7 TCSYLVIO_001495 ↔ TCSYLVIO_009791	OG7
LpyrH10_01_9430 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_353550.1 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_006188 OG7 LdBPK_261400.1 ↔ LdBPK_301150.1	OG7
LpyrH10_25_1710 ⚠ hypothetical protein, conserved, putative mit	—	OG7 TCSYLVIO_007259 ↔ TCSYLVIO_009791 OG7 LdBPK_070440.1 ↔ LdBPK_200280.1	OG7
LpyrH10_11_0930 ⚠ dynein arm light chain, putative	—	OG7 LdBPK_070440.1 ↔ LdBPK_211260.1 OG7 LdBPK_070440.1 ↔ LdBPK_261100.1 OG7 TCSYLVIO_001495 ↔ TCSYLVIO_009791	OG7
LpyrH10_14_1310 ⚠ dynein arm light chain, putative	—	OG7 LdBPK_070440.1 ↔ LdBPK_211260.1 OG7 LdBPK_070440.1 ↔ LdBPK_261100.1 OG7 TCSYLVIO_001495 ↔ TCSYLVIO_009791	OG7
LpyrH10_02_0380 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070440.1 ↔ LdBPK_320320.1 OG7 TCSYLVIO_006103 ↔ TCSYLVIO_009791	OG7
LpyrH10_37_0180 ⚠ paraflagellar rod protein, putative	—	OG7 LdBPK_050920.1 ↔ LdBPK_070440.1	OG7
LpyrH10_10_2340 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070440.1 ↔ LdBPK_251920.1	OG7
LpyrH10_03_3880 ⚠ Hypothetical protein, conserved	—	OG7 LdBPK_070440.1 ↔ LdBPK_230020.1	OG7
LpyrH10_23_0760 ⚠ Hypothetical protein, conserved (GO function:	—	OG7 LdBPK_070440.1 ↔ LdBPK_171240.1 OG7 LdBPK_120470.1 ↔ LdBPK_161180.1	OG7
LpyrH10_05_4190 ⚠ target of rapamycin kinase (TOR) kinase 3, pu	—	OG7 LdBPK_070440.1 ↔ LdBPK_366580.1 OG7 LdBPK_070440.1 ↔ LdBPK_201140.1 OG7 LdBPK_020100.1 ↔ LdBPK_070440.1	OG7
LpyrH10_32_1000 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_070440.1 ↔ LdBPK_310140.1	OG7
LpyrH10_24_1180 ⚠ hypothetical protein	—	OG7 LdBPK_041060.1 ↔ LdBPK_301150.1	OG7
LpyrH10_04_0670 ⚠ Dna-directed RNA polymerase, alpha subunit, p	—	OG7 LdBPK_190660.1 ↔ LdBPK_301150.1	OG7
LpyrH10_35_0530 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003527 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_009791	OG7
LpyrH10_14_1380 ⚠ T-complex protein 1, delta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_02_1200 ⚠ chaperonin containing t-complex protein, puta	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_07_1540 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_01_6200 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_03_2130 ⚠ T-complex protein 1, gamma subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_02_3770 ⚠ chaperonin alpha subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_20_0060 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_09_1870 ⚠ Proteasome alpha 1 subunit, putative, putativ	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003527 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_009791	OG7
LpyrH10_15_0340 ⚠ proteasome 26S non-ATPase subunit 9, putative	—	OG7 TCSYLVIO_001198 ↔ TCSYLVIO_009791	OG7
LpyrH10_22_0900 ⚠ Hypothetical protein, conserved	—	OG7 LdBPK_100630.1 ↔ LdBPK_301150.1	OG7
LpyrH10_06_5180 ⚠ Chaperonin, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
LpyrH10_14_2430 ⚠ histone deacetylase, putative	—	OG7 LdBPK_081300.1 ↔ LdBPK_301150.1	OG7
LpyrH10_07_0240 ⚠ Hypothetical protein, conserved	—	OG7 LdBPK_050190.1 ↔ LdBPK_070440.1	OG7
LpyrH10_03_1900 ⚠ DNA polymerase theta (helicase domain only),	—	OG7 LdBPK_130390.1 ↔ LdBPK_301150.1	OG7
LpyrH10_02_1630 ⚠ DEAD/DEAH box helicase-like protein, putative	—	OG7 LdBPK_130390.1 ↔ LdBPK_301150.1	OG7
LpyrH10_20_1440 ⚠ RNA helicase, putative	—	OG7 LdBPK_130390.1 ↔ LdBPK_301150.1	OG7
LpyrH10_14_2360 ⚠ 20S proteasome subunit alpha 5, (putative)	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003527 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_009791	OG7
LpyrH10_21_1010 ⚠ ATP-dependent RNA helicase, putative	—	OG7 LdBPK_130390.1 ↔ LdBPK_301150.1	OG7
LpyrH10_28_0260 ⚠ histone deacetylase, putative	—	OG7 LdBPK_081300.1 ↔ LdBPK_301150.1	OG7
LpyrH10_28_0730 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_080430.1 ↔ LdBPK_301150.1	OG7
LpyrH10_22_1040 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_100740.1 ↔ LdBPK_161180.1	OG7
LpyrH10_03_1170 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_061020.1 ↔ LdBPK_301150.1	OG7
LpyrH10_01_7250 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003527 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_009791	OG7
LpyrH10_04_1820 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_191020.1 ↔ LdBPK_300970.1	OG7
LpyrH10_29_1170 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_313100.1 ↔ LdBPK_355080.1	OG7
LpyrH10_18_0280 ⚠ Proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003527 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_009791	OG7

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