LpyrH10_18_0790

aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17

Leptomonas pyrrhocoris H10 OG6: OG6_142599 OG7: OG7_0003405 315 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 315 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LpyrH10_25_0620 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LpyrH10_23_0440 ⚠ Aminoacylase, putativen-acyl-l-amino acid ami	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_23_0460 ⚠ Aminoacylase, putativen-acyl-l-amino acid ami	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_25_0070 ⚠ aminoacylase, putative,N-acyl-L-amino acid am	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_01_8800 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_04_4050 ⚠ Aminoacylase, putativen-acyl-l-amino acid ami	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_33_0550 ⚠ Dna-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
LpyrH10_24_0510 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LpyrH10_04_3370 ⚠ Hypothetical protein, conserved	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG6 LdBPK_110630.1 ↔ LdBPK_300810.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG7 LdBPK_110630.1 ↔ LdBPK_300810.1	Both
LpyrH10_01_2530 ⚠ NADH-dependent fumarate reductase-like protei	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LpyrH10_14_1160 ⚠ aspartyl-tRNA synthetase, putative, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LpyrH10_23_0450 ⚠ Aminoacylase, putativen-acyl-l-amino acid ami	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_25_0080 ⚠ aminoacylase, putative,N-acyl-L-amino acid am	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_06_3530 ⚠ isoleucyl-tRNA synthetase, putative, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LpyrH10_04_3020 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LpyrH10_12_1790 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_04_3120 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LpyrH10_02_7700 ⚠ ribonuclease II-like protein, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LpyrH10_24_0300 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LpyrH10_01_2930 ⚠ NADH-dependent fumarate reductase, putative,	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LpyrH10_01_2940 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LpyrH10_05_2510 ⚠ asparaginyl-tRNA synthetase, putative, putati	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG6 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 +1 more	Both
LpyrH10_23_0430 ⚠ Aminoacylase, putativen-acyl-l-amino acid ami	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_28_0740 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
LpyrH10_25_0630 ⚠ calpain-like cysteine peptidase, putative,cys	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LpyrH10_30_0420 ⚠ flavoprotein subunit-like protein	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LpyrH10_02_7830 ⚠ Rrp44p homologue, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_280470.1 OG6 LdBPK_110640.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 +2 more	Both
LpyrH10_06_1750 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_110630.1 ↔ LdBPK_364240.1 OG6 LdBPK_110640.1 ↔ LdBPK_364240.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 LdBPK_110630.1 ↔ LdBPK_364240.1 +2 more	Both
LpyrH10_25_0090 ⚠ aminoacylase, putative,N-acyl-L-amino acid am	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +1 more	OG6
LpyrH10_05_1700 ⚠ hypothetical protein, conserved,inositol 5-ph	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007569	OG7
LpyrH10_32_0720 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_110640.1 ↔ LdBPK_310320.1	OG7
LpyrH10_01_3560 ⚠ ubiquitin hydrolase, putative	—	OG7 LdBPK_332700.1 ↔ LdBPK_343890.1	OG7
LpyrH10_01_4530 ⚠ ubiquitin hydrolase, putative,cysteine peptid	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005374	OG7
LpyrH10_01_9250 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_110640.1 ↔ LdBPK_180610.1	OG7
LpyrH10_24_0180 ⚠ RNA pseudouridylate synthase-like protein	—	OG7 LdBPK_110630.1 ↔ LdBPK_261140.1 OG7 LdBPK_110640.1 ↔ LdBPK_261140.1 OG7 LdBPK_261140.1 ↔ LdBPK_332700.1	OG7
LpyrH10_14_0610 ⚠ la RNA binding protein, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_006827	OG7
LpyrH10_10_2650 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_006404	OG7
LpyrH10_05_4150 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_001670	OG7
LpyrH10_06_4330 ⚠ flagellum transition zone component, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_366480.1 OG7 LdBPK_110640.1 ↔ LdBPK_366480.1 OG7 LdBPK_332700.1 ↔ LdBPK_366480.1	OG7
LpyrH10_02_5200 ⚠ Serine hydroxymethyltransferaseserine hydroxy	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_010621	OG7
LpyrH10_22_1260 ⚠ FKBP-type peptidyl-prolyl cis-trans isomerase	—	OG7 LdBPK_110630.1 ↔ LdBPK_291330.1 OG7 LdBPK_110640.1 ↔ LdBPK_291330.1 OG7 LdBPK_291330.1 ↔ LdBPK_332700.1	OG7
LpyrH10_26_0560 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007569	OG7
LpyrH10_21_0540 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7
LpyrH10_42_0010 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LpyrH10_45_0040 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LpyrH10_05_2820 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7
LpyrH10_01_6530 ⚠ elongation factor 1-alpha, putative,hsp70 sub	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LpyrH10_07_1560 ⚠ ubiquitin hydrolase, putative,cysteine peptid	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005374	OG7
LpyrH10_06_4790 ⚠ Hypothetical protein, conserved	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7
LpyrH10_21_0570 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7

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