LpyrH10_21_0120

cystathionine beta-synthase (CYSB)
Leptomonas pyrrhocoris H10 OG6: OG6_100154 OG7: OG7_0002172 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LpyrH10_30_0400 ⚠
phosphoacetylglucosamine mutase-like protein,
— +2 more Both
LpyrH10_03_2900 ⚠
acetyl-CoA synthetase, putative
— +1 more Both
LpyrH10_03_4680 ⚠
Trypanothione synthetase, putative
— Both
LpyrH10_01_8760 ⚠
asparagine synthetase a, putative,aspartate--
— Both
LpyrH10_03_2920 ⚠
3-ketoacyl-CoA thiolase, putative, putative m
— Both
LpyrH10_03_4450 ⚠
branched-chain amino acid aminotransferase, p
— Both
LpyrH10_03_4430 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LpyrH10_25_1330 ⚠
cytidine triphosphate synthase, putative,CTP
— Both
LpyrH10_08_3340 ⚠
unspecified product
— Both
LpyrH10_03_4470 ⚠
branched-chain amino acid aminotransferase, p
— Both
LpyrH10_01_1280 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LpyrH10_08_3330 ⚠
Inosine-adenosine-guanosine-nucleoside hydrol
— Both
LpyrH10_08_2660 ⚠
aminopeptidase, putative
— Both
LpyrH10_11_2470 ⚠
hypothetical protein, conserved, putative mit
— Both
LpyrH10_06_4890 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LpyrH10_16_1440 ⚠
hypothetical protein, conserved
— OG6
LpyrH10_04_3900 ⚠
Pyridoxal kinase, putative
— Both
LpyrH10_17_0380 ⚠
threonine synthase, putative
— Both
LpyrH10_03_4480 ⚠
branched-chain amino acid aminotransferase, p
— Both
LpyrH10_02_4690 ⚠
heat shock protein 70, putative, putative mit
— OG6
LpyrH10_02_4740 ⚠
heat-shock protein hsp70, putative, putative
— OG6
LpyrH10_02_6730 ⚠
glucose-regulated protein 78, putative
— OG6
LpyrH10_01_9200 ⚠
heat shock protein 70-related protein
— OG6
LpyrH10_02_4760 ⚠
heat-shock protein hsp70, putative, putative
— OG6
LpyrH10_02_4730 ⚠
heat-shock protein hsp70, putative, putative
— OG6
LpyrH10_02_4750 ⚠
heat-shock protein hsp70, putative, putative
— OG6
LpyrH10_05_3040 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LpyrH10_07_1090
hypothetical protein, conserved
— OG7
LpyrH10_09_2830 ⚠
tyrosine aminotransferase, putative
— OG7
LpyrH10_06_2220 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LpyrH10_23_0150 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LpyrH10_03_3350 ⚠
trypanothione synthetase, putative
— OG7
LpyrH10_10_2950 ⚠
glutathionylspermidine synthase, putative
— OG7
LpyrH10_01_2050 ⚠
Serine palmitoyltransferase, putative
— OG7
LpyrH10_38_0400 ⚠
nonspecific lipid-transfer protein, putative,
— OG7
LpyrH10_03_5160 ⚠
D-alanyl-glycyl endopeptidase-like protein,cy
— OG7
LpyrH10_03_5240 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LpyrH10_05_3970 ⚠
serine palmitoyltransferase-like protein
— OG7
LpyrH10_24_0670 ⚠
spermidine synthase, putative, putative mitoc
— Both
LpyrH10_10_1950 ⚠
Hypothetical protein, conserved
— OG7
LpyrH10_02_4430 ⚠
cyclic nucleotide-binding protein-like protei
— OG7
LpyrH10_05_2020 ⚠
hypothetical protein, conserved
— OG7
LpyrH10_32_0930 ⚠
Nucleolar protein, putative
— OG7
LpyrH10_08_2390 ⚠
hypothetical protein, conserved
— OG7
LpyrH10_02_6020 ⚠
hypothetical protein, conserved
— OG7
LpyrH10_31_0920 ⚠
hypothetical protein, conserved, putative mit
— OG7
LpyrH10_14_0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LpyrH10_20_1030 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LpyrH10_05_1910 ⚠
hypothetical protein, conserved
— Both
LpyrH10_04_6760 ⚠
hypothetical protein, conserved, putative mit
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.