TRSC58_00219

translation initiation factor eIF-2B alpha subunit
Trypanosoma rangeli SC58 OG6: OG6_102141 OG7: OG7_0001817 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TRSC58_00581
OSM3-like kinesin
— OG6
TRSC58_05885 ⚠
cyclic nucleotide-binding protein
— OG7
TRSC58_04549 ⚠
structural maintenance of chromosome 3 protei
— OG7
TRSC58_01520 ⚠
dynein arm light chain
— OG7
TRSC58_06439 ⚠
phosphatidylinositol 3-kinase
— OG7
TRSC58_05174 ⚠
hypothetical protein
— OG7
TRSC58_03448 ⚠
tubulin-specific chaperone
— OG7
TRSC58_00959 ⚠
dynein arm light chain
— OG7
TRSC58_02406 ⚠
AAA ATPase
— Both
TRSC58_04994 ⚠
hypothetical protein
— OG7
TRSC58_06561 ⚠
phosphatidylinositol kinase related TOR1
— Both
TRSC58_06815 ⚠
ubiquitin-protein ligase
— Both
TRSC58_06676 ⚠
phosphatidylinositol kinase related TOR2
— Both
TRSC58_05506 ⚠
immunodominant antigen
— Both
TRSC58_01320 ⚠
hypothetical protein
— Both
TRSC58_06235 ⚠
hypothetical protein
— Both
TRSC58_02424
protein kinase
— OG6
TRSC58_03372 ⚠
hypothetical protein
— OG7
TRSC58_04825 ⚠
hypothetical protein
— OG7
TRSC58_03827 ⚠
hypothetical protein
— OG7
TRSC58_06826 ⚠
hypothetical protein
— OG7
TRSC58_06798 ⚠
hypothetical protein
— OG7
TRSC58_05365 ⚠
hypothetical protein
— OG7
TRSC58_01768 ⚠
hypothetical protein
— OG7
TRSC58_06941 ⚠
hypothetical protein
— OG7
TRSC58_03578 ⚠
hypothetical protein
— OG7
TRSC58_00545 ⚠
hypothetical protein
— Both
TRSC58_00692 ⚠
hypothetical protein
— OG7
TRSC58_04269 ⚠
translation initiation factor eIF2B delta sub
— OG7
TRSC58_03118 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TRSC58_01343 ⚠
hypothetical protein
— OG7
TRSC58_06093 ⚠
phosphatidylinositol kinase related TOR-like
— OG7
TRSC58_06491 ⚠
phosphatidylinositol kinase related ATR
— OG7
TRSC58_03633 ⚠
protein kinase A regulatory subunit
— OG7
TRSC58_06927 ⚠
5'-3' exoribonuclease 1
— Both
TRSC58_06765 ⚠
hypothetical protein
— Both
TRSC58_00306 ⚠
hypothetical protein
— Both
TRSC58_07157 ⚠
transcriptional regulatory protein NOT1
— Both
TRSC58_03310 ⚠
hypothetical protein
— Both
TRSC58_06527 ⚠
phosphatidylinositol kinase related protein A
— Both
TRSC58_03466 ⚠
translation initiation factor eIF-2B beta sub
— Both
TRSC58_06323 ⚠
hypothetical protein
— Both
TRSC58_02429 ⚠
5'-3' exoribonuclease 1
— Both
TRSC58_02489 ⚠
leucine-rich repeat protein (LRRP)
— Both
TRSC58_01868 ⚠
5'-3' exoribonuclease 2
— Both
TRSC58_05615 ⚠
hypothetical protein
— Both
TRSC58_03979 ⚠
hypothetical protein
— Both
TRSC58_06029 ⚠
hypothetical protein
— Both
TRSC58_04558 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TRSC58_03818 ⚠
hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.