TRSC58_00957

DNA ligase I

Trypanosoma rangeli SC58 OG6: OG6_100906 OG7: OG7_0002598 162 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 162 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_01485 hypothetical protein	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004471 OG6 LdBPK_030750.1 ↔ LdBPK_303490.1 OG7 LdBPK_030750.1 ↔ LdBPK_303490.1 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004471	Both
TRSC58_03487 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_009102 OG7 LdBPK_303490.1 ↔ LdBPK_311970.1	Both
TRSC58_02059 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_009102 OG7 LdBPK_303490.1 ↔ LdBPK_311970.1	OG7
TRSC58_05416 ⚠ rab6 GTPase activating protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004663	OG7
TRSC58_07076 ⚠ dipeptidyl-peptidase 8-like serine peptidase	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007536	Both
TRSC58_00868 hypothetical protein	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004409 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004409	Both
TRSC58_04909 ⚠ asparaginyl-tRNA synthetase	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_003867	Both
TRSC58_02832 hypothetical protein	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_005710	Both
TRSC58_07732 leucyl-tRNA synthetase	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007991	Both
TRSC58_06449 ⚠ rab-like GTPase activating protein	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004663 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004663	Both
TRSC58_05052 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_003375	Both
TRSC58_02800 hypothetical protein	—	OG6 TCSYLVIO_003285 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_003285 ↔ TCSYLVIO_003375	Both
TRSC58_03913 S-adenosylmethionine decarboxylase proenzyme	—	OG6 TCSYLVIO_003342 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_003342 ↔ TCSYLVIO_003375	Both
TRSC58_03822 phosphonopyruvate decarboxylase	—	OG6 TCSYLVIO_002596 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_002596 ↔ TCSYLVIO_003375	Both
TRSC58_04099 ⚠ translation initiation factor IF-2	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_003375	Both
TRSC58_02322 casein kinase II, alpha chain	—	OG6 LdBPK_020330.1 ↔ LdBPK_303490.1	OG6
TRSC58_00610 hypothetical protein	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_003375	Both
TRSC58_03727 alanyl-tRNA synthetase	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_003375	Both
TRSC58_06650 ⚠ ribonuclease II-like protein	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_003375 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003375	Both
TRSC58_03281 replication factor A, 51kDa subunit	—	OG6 LdBPK_281940.1 ↔ LdBPK_303490.1 OG7 LdBPK_281940.1 ↔ LdBPK_303490.1	Both
TRSC58_00546 ⚠ hypothetical protein	—	OG6 LdBPK_220940.1 ↔ LdBPK_303490.1 OG7 LdBPK_220940.1 ↔ LdBPK_303490.1	Both
TRSC58_03268 ⚠ hypothetical protein	—	OG6 LdBPK_220940.1 ↔ LdBPK_303490.1 OG7 LdBPK_220940.1 ↔ LdBPK_303490.1	Both
TRSC58_01090 hypothetical protein	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_003375	Both
TRSC58_02848 hypothetical protein	—	OG6 TCSYLVIO_000215 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_000215 ↔ TCSYLVIO_003375	Both
TRSC58_03555 acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003375	Both
TRSC58_04624 ⚠ RRP44p like proteinue	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003375	OG7
TRSC58_00367 ⚠ mitochondrial exoribonuclease DSS-1	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_003375	OG7
TRSC58_06233 ⚠ cytochrome b-domain protein	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_003375	OG7
TRSC58_01796 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_003375	OG7
TRSC58_06526 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_003375	OG7
TRSC58_03133 oxidoreductase	—	OG7 LdBPK_100610.1 ↔ LdBPK_303490.1	OG7
TRSC58_00896 hypothetical protein	—	OG7 LdBPK_262090.1 ↔ LdBPK_303490.1	OG7
TRSC58_00916 ribonuclease mar1	—	OG7 LdBPK_080330.1 ↔ LdBPK_303490.1	OG7
TRSC58_00815 ⚠ tubulin tyrosine ligase	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_03095 ⚠ hypothetical protein	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_03353 ⚠ tubulin tyrosine ligase	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_01345 ⚠ hypothetical protein	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_03126 ⚠ tubulin-tyrosine ligase-like protein	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_03244 ⚠ tubulin-tyrosine ligase-like protein	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_00878 ⚠ tubulin-tyrosine ligase	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_02376 ⚠ tubulin-tyrosine ligase-like protein	—	OG7 LdBPK_200800.1 ↔ LdBPK_303490.1	OG7
TRSC58_04869 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004998	OG7
TRSC58_00374 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007685	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_010148	OG7
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_010148	OG7
TRSC58_04263 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_005414	OG7
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_010148	OG7
TRSC58_05583 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_003867	OG7
TRSC58_01959 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_003867	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003375 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_010148	OG7

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