TRSC58_00972

pyruvate dehydrogenase (lipoamide) kinase

Trypanosoma rangeli SC58 OG6: OG6_146742 OG7: OG7_0002830 144 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 144 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_06996 ⚠ hypothetical protein	—	OG6 LdBPK_230660.1 ↔ LdBPK_240010.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 +1 more	Both
TRSC58_04704 ⚠ cysteinyl-tRNA synthetase	—	OG6 LdBPK_120255.1 ↔ LdBPK_240010.1 OG6 TCSYLVIO_001571 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977 +1 more	Both
TRSC58_04153 ⚠ ribonuclease	—	OG6 LdBPK_230660.1 ↔ LdBPK_240010.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 +1 more	Both
TRSC58_02550 ⚠ developmentally regulated phosphoprotein	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_007262 OG6 Tb927.1.1000 ↔ Tb927.11.4780 OG7 Tb927.1.1000 ↔ Tb927.11.4780 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007262	Both
TRSC58_04909 ⚠ asparaginyl-tRNA synthetase	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_003867 OG6 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 +1 more	Both
TRSC58_05704 ⚠ hypothetical protein	—	OG7 Tb927.1.1000 ↔ Tb927.11.4780 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007262	OG7
TRSC58_06488 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
TRSC58_03792 ⚠ phenylalanyl-tRNA synthetase	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_005548 OG6 LdBPK_191010.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005548 +1 more	Both
TRSC58_02324 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
TRSC58_01959 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
TRSC58_05583 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
TRSC58_02762 ⚠ aspartyl aminopeptidase	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_004406 OG6 LdBPK_240010.1 ↔ LdBPK_292470.1 OG7 LdBPK_240010.1 ↔ LdBPK_292470.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_004406	Both
TRSC58_06662 ⚠ hypothetical protein	—	OG6 LdBPK_240010.1 ↔ LdBPK_240500.1 OG7 LdBPK_240010.1 ↔ LdBPK_240500.1	Both
TRSC58_01539 ⚠ hypothetical protein	—	OG7 LdBPK_091450.1 ↔ LdBPK_200310.1	OG7
TRSC58_06407 ⚠ hypothetical protein	—	OG6 LdBPK_240010.1 ↔ LdBPK_240660.1 OG7 LdBPK_240010.1 ↔ LdBPK_240660.1	Both
TRSC58_01364 hypothetical protein	—	OG6 LdBPK_240010.1 ↔ LdBPK_291830.1	OG6
TRSC58_05067 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_007262	Both
TRSC58_02673 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001778 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_001778	OG7
TRSC58_03293 ⚠ aminopeptidase	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_001670	OG7
TRSC58_05751 ⚠ hypothetical protein	—	OG7 LdBPK_030950.1 ↔ LdBPK_200310.1	OG7
TRSC58_00619 ⚠ hypothetical protein	—	OG7 LdBPK_030950.1 ↔ LdBPK_200310.1	OG7
TRSC58_06798 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_240010.1	OG7
TRSC58_06323 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_240010.1	OG7
TRSC58_06826 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_240010.1	OG7
TRSC58_04825 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_240010.1	OG7
TRSC58_06815 ⚠ ubiquitin-protein ligase	—	OG7 LdBPK_161180.1 ↔ LdBPK_240010.1	OG7
TRSC58_03021 ⚠ 6-phosphofructo-2-kinase/fructose-2, 6-biphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
TRSC58_03008 ⚠ 6-phosphofructo-2-kinase/fructose-2, 6-biphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
TRSC58_04064 ⚠ fructose-6-phosphate2-kinase/fructose-2, 6-bi	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
TRSC58_04863 ⚠ ubiquitin hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005373 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005374	OG7
TRSC58_02088 ⚠ ubiquitin hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005373 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005374	OG7
TRSC58_04494 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_06485 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_05272 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_06663 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_01331 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_05837 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_291830.1	OG7
TRSC58_06727 ⚠ hypothetical protein	—	OG7 LdBPK_240010.1 ↔ LdBPK_353550.1	OG7
TRSC58_06361 ⚠ hypothetical protein	—	OG7 TCSYLVIO_003670 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003670 OG7 TCSYLVIO_007262 ↔ TCSYLVIO_010263 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_009456	OG7
TRSC58_06424 ⚠ retrotransposon hot spot (RHS) protein	—	OG7 TCSYLVIO_003670 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003670 OG7 TCSYLVIO_007262 ↔ TCSYLVIO_010263 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_009456	OG7
TRSC58_06675 ⚠ cytoskeleton-associated protein CAP5.5	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007342 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007342	OG7
TRSC58_06393 ⚠ hypothetical protein	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007569 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007569	OG7
TRSC58_01604 ⚠ heat shock protein	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007262 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_009400 +2 more	OG7
TRSC58_02857 ⚠ calpain-like cysteine peptidase	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007342 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007342	OG7
TRSC58_03474 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006116	OG7
TRSC58_05157 ⚠ hypothetical protein	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007569 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007569	OG7
TRSC58_01574 ⚠ hypothetical protein	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007569 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007569	OG7
TRSC58_05629 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006901	OG7
TRSC58_05831 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006116	OG7
TRSC58_00717 ⚠ lipin	—	OG7 TCSYLVIO_001856 ↔ TCSYLVIO_007262	OG7

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