TRSC58_01647

multidrug resistance protein E

Trypanosoma rangeli SC58 OG6: OG6_100026 OG7: OG7_0000689 47 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 47 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_01773 ⚠ soluble N-ethylmaleimide sensitive factor (NS	—	OG6 TCSYLVIO_005376 ↔ TCSYLVIO_007542 OG7 TCSYLVIO_005376 ↔ TCSYLVIO_007542	Both
TRSC58_03652 ⚠ hypothetical protein	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_07012 ⚠ hexose transporter	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_07149 ⚠ hexose transporter	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_06550 ⚠ hexose transporter	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_03998 ⚠ hypothetical protein	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_01436 ⚠ hexose transporter	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_01406 ⚠ serine/threonine protein phosphatase-like pro	—	OG6 Tb927.1.4050 ↔ Tb927.4.4490 OG6 Tb927.1.4050 ↔ Tb927.8.2160	OG6
TRSC58_05135 ⚠ protein phosphatase 1, regulatory subunit	—	OG6 TCSYLVIO_002097 ↔ TCSYLVIO_007542 OG7 TCSYLVIO_002097 ↔ TCSYLVIO_007542	Both
TRSC58_01526 ⚠ folate/pteridine transporter	—	OG6 Tb927.10.9080 ↔ Tb927.4.4490 OG6 Tb927.10.9080 ↔ Tb927.8.2160 OG7 Tb927.10.9080 ↔ Tb927.4.4490 OG7 Tb927.10.9080 ↔ Tb927.8.2160	Both
TRSC58_04695 ⚠ folate/pteridine transporter	—	OG6 Tb927.10.9080 ↔ Tb927.4.4490 OG6 Tb927.10.9080 ↔ Tb927.8.2160 OG7 Tb927.10.9080 ↔ Tb927.4.4490 OG7 Tb927.10.9080 ↔ Tb927.8.2160	Both
TRSC58_06916 ⚠ folate/pteridine transporter	—	OG6 Tb927.10.9080 ↔ Tb927.4.4490 OG6 Tb927.10.9080 ↔ Tb927.8.2160 OG7 Tb927.10.9080 ↔ Tb927.4.4490 OG7 Tb927.10.9080 ↔ Tb927.8.2160	Both
TRSC58_07092 ⚠ hexose transporter	—	OG6 Tb927.10.8530 ↔ Tb927.4.4490 OG6 Tb927.10.8530 ↔ Tb927.8.2160 OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	Both
TRSC58_01668 ⚠ sugar transporter	—	OG7 Tb927.10.8530 ↔ Tb927.4.4490 OG7 Tb927.10.8530 ↔ Tb927.8.2160	OG7
TRSC58_06361 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_06424 ⚠ retrotransposon hot spot (RHS) protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_07003 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_01499 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_07193 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_07112 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_06890 ⚠ hypothetical protein	—	OG7 TCSYLVIO_006446 ↔ TCSYLVIO_007542	OG7
TRSC58_01787 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004180 ↔ TCSYLVIO_007542	OG7
TRSC58_06808 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004180 ↔ TCSYLVIO_007542	OG7
TRSC58_00002 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004180 ↔ TCSYLVIO_007542	OG7
TRSC58_04923 ⚠ hypothetical protein	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160	OG6
TRSC58_00443 ⚠ hypothetical protein	—	OG6 LdBPK_120530.1 ↔ LdBPK_311460.1 OG7 LdBPK_120530.1 ↔ LdBPK_311460.1	Both
TRSC58_07020 ⚠ hypothetical protein	—	OG6 Tb927.4.4490 ↔ Tb927.8.2160 OG7 Tb927.4.4490 ↔ Tb927.8.2160	Both
TRSC58_06843 ⚠ multidrug resistance protein A	—	OG6 Tb927.4.4490 ↔ Tb927.8.2160 OG7 Tb927.4.4490 ↔ Tb927.8.2160	Both
TRSC58_02255 ⚠ calcium motive p-type ATPase	—	OG6 Tb927.8.2160 ↔ Tb927.9.15460 OG6 Tb927.4.4490 ↔ Tb927.9.15460 OG7 Tb927.8.2160 ↔ Tb927.9.15460 OG7 Tb927.4.4490 ↔ Tb927.9.15460	Both
TRSC58_06343 ⚠ ABC transporter	—	OG6 Tb927.8.2160 ↔ Tb927.9.6310 OG6 Tb927.4.4490 ↔ Tb927.9.6310 OG6 Tb927.10.7700 ↔ Tb927.4.4490 OG6 Tb927.10.7700 ↔ Tb927.8.2160 +4 more	Both
TRSC58_05484 ⚠ hypothetical protein	—	OG6 Tb927.8.2160 ↔ Tb927.9.6310 OG6 Tb927.4.4490 ↔ Tb927.9.6310 OG6 Tb927.10.7700 ↔ Tb927.4.4490 OG6 Tb927.10.7700 ↔ Tb927.8.2160 +4 more	Both
TRSC58_07117 ⚠ ABC transporter	—	OG6 Tb927.8.2160 ↔ Tb927.9.6310 OG6 Tb927.4.4490 ↔ Tb927.9.6310 OG6 Tb927.10.7700 ↔ Tb927.4.4490 OG6 Tb927.10.7700 ↔ Tb927.8.2160 +4 more	Both
TRSC58_05607 ⚠ ATP-binding protein cassette protein	—	OG6 Tb927.8.2160 ↔ Tb927.9.6310 OG6 Tb927.4.4490 ↔ Tb927.9.6310 OG6 Tb927.10.7700 ↔ Tb927.4.4490 OG6 Tb927.10.7700 ↔ Tb927.8.2160 +4 more	Both
TRSC58_03782 ⚠ ABC transporter	—	OG6 Tb927.8.2160 ↔ Tb927.9.6310 OG6 Tb927.4.4490 ↔ Tb927.9.6310 OG6 Tb927.10.7700 ↔ Tb927.4.4490 OG6 Tb927.10.7700 ↔ Tb927.8.2160 +4 more	Both
TRSC58_06921 ⚠ multidrug resistance protein E	—	OG6 Tb927.4.4490 ↔ Tb927.8.2160 OG7 Tb927.4.4490 ↔ Tb927.8.2160	Both
TRSC58_04472 ⚠ ADP-ribosylation factor GTPase activating pro	—	OG6 TCSYLVIO_004180 ↔ TCSYLVIO_007542 OG7 TCSYLVIO_004180 ↔ TCSYLVIO_007542	Both
TRSC58_06642 ⚠ phosphoinositide-specific phospholipase C	—	OG6 Tb927.11.5970 ↔ Tb927.4.4490 OG6 Tb927.11.5970 ↔ Tb927.8.2160 OG7 Tb927.11.5970 ↔ Tb927.4.4490 OG7 Tb927.11.5970 ↔ Tb927.8.2160	Both
TRSC58_01997 ⚠ P-type H+-ATPase	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
TRSC58_07115 ⚠ H+-transporting ATPase	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
TRSC58_04120 ⚠ P-type H+-ATPase	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
TRSC58_02759 ⚠ P-type H+-ATPase	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
TRSC58_03591 ⚠ hypothetical protein	—	OG6 TCSYLVIO_007542 ↔ TCSYLVIO_009973 OG7 TCSYLVIO_007542 ↔ TCSYLVIO_009973	Both
TRSC58_00699 ⚠ hypothetical protein	—	OG6 Tb11.1390 ↔ Tb927.4.4490 OG6 Tb11.1390 ↔ Tb927.8.2160 OG7 Tb11.1390 ↔ Tb927.4.4490 OG7 Tb11.1390 ↔ Tb927.8.2160	Both
TRSC58_02684 ⚠ monoglyceride lipase	—	OG6 Tb927.4.4360 ↔ Tb927.4.4490 OG6 Tb927.4.4360 ↔ Tb927.8.2160 OG7 Tb927.4.4360 ↔ Tb927.4.4490 OG7 Tb927.4.4360 ↔ Tb927.8.2160	Both
TRSC58_06500 ⚠ acylglycerol lipase	—	OG6 Tb927.4.4360 ↔ Tb927.4.4490 OG6 Tb927.4.4360 ↔ Tb927.8.2160 OG7 Tb927.4.4360 ↔ Tb927.4.4490 OG7 Tb927.4.4360 ↔ Tb927.8.2160	Both
TRSC58_01912 ⚠ copper homeostasis protein	—	OG6 TCSYLVIO_001568 ↔ TCSYLVIO_007542 OG7 TCSYLVIO_001568 ↔ TCSYLVIO_007542	Both
TRSC58_07175 ⚠ hypothetical protein	—	OG6 Tb927.11.6040 ↔ Tb927.4.4490 OG6 Tb927.11.6040 ↔ Tb927.8.2160	OG6