Tb927.11.1540

isovaleryl-CoA dehydrogenase
Trypanosoma brucei brucei TREU927 OG6: OG6_102105 OG7: OG7_0001034 Source organism 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Cross-organism orthology
Defaulting to same-organism data. Applies on "Apply filters".
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
Tb927.10.6190
aldehyde dehydrogenase, putative
T.brucei_2016_Gazestani — n/a
Tb927.11.6280
pyruvate phosphate dikinase
T.brucei_2016_Gazestani — n/a
Tb927.10.14140
pyruvate kinase 1
T.brucei_2016_Gazestani — n/a
Tb927.8.6170
transketolase, putative
T.brucei_2016_Gazestani — n/a
Tb927.8.1990
peroxidoxin
T.brucei_2016_Gazestani — n/a
Tb927.10.2490
glucose-6-phosphate 1-dehydrogenase
T.brucei_2016_Gazestani — n/a
Tb927.11.3650
adenylosuccinate synthetase, putative
T.brucei_2016_Gazestani — n/a
Tb927.9.4200
fatty acyl CoA synthetase 2
T.brucei_2016_Gazestani — n/a
Tb927.9.9820
glyceraldehyde-3-phosphate dehydrogenase, put
T.brucei_2016_Gazestani — n/a
Tb927.7.4570
inosine-guanine nucleoside hydrolase
T.brucei_2016_Gazestani — n/a
Tb927.7.1910
pyridoxal phosphate containing glycine decarb
T.brucei_2016_Gazestani — n/a
Tb927.9.5210
glutaminyl-tRNA synthetase, putative
T.brucei_2016_Gazestani — n/a
Tb927.8.2050
GDP-mannose pyrophosphorylase
T.brucei_2016_Gazestani — n/a
Tb927.11.2690
Succinyl-CoA:3-ketoacid coenzyme A transferas
T.brucei_2016_Gazestani — n/a
Tb927.1.3830
glucose-6-phosphate isomerase, glycosomal
T.brucei_2016_Gazestani — n/a
Tb927.4.1360
Glucose-6-phosphate 1-epimerase, putative
T.brucei_2016_Gazestani — n/a
Tb927.7.4970
glutamine synthetase, putative
T.brucei_2016_Gazestani — n/a
Tb927.6.4840
S-adenosylmethionine synthetase
T.brucei_2016_Gazestani — n/a
Tb927.11.16770
glucosamine-6-phosphate isomerase, putative
T.brucei_2016_Gazestani — n/a
Tb927.5.4560
guanase, putative, guanine deaminase, putativ
T.brucei_2016_Gazestani — n/a
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.