TcCLB.503841.40

Actin 4, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_458889 OG7: OG7_0000774 12 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 12 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509819.30 ⚠
septum formation inhibitor, Maf-like protein,
— OG7
TcCLB.509127.104 ⚠
ARP2/3 complex subunit, putative
— OG7
TcCLB.507129.10 ⚠
Actin 2
— OG7
TcCLB.508277.330 ⚠
actin-like protein, putative
— OG7
TcCLB.510127.79 ⚠
actin 3, putative (fragment)
— OG7
TcCLB.508277.260 ⚠
actin-related protein 3, putative
— OG7
TcCLB.508951.29 ⚠
actin-like protein, putative
— OG7
TcCLB.506865.10 ⚠
ARP2/3 complex subunit, putative
— OG7
TcCLB.510963.70 ⚠
ARP2/3 complex subunit, putative
— OG7
TcCLB.510719.110 ⚠
actin-like protein, putative
— OG7
TcCLB.506733.50 ⚠
actin-like protein, putative
— OG7
TcCLB.511361.40 ⚠
actin-related protein 2, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.