TcCLB.504153.170

NUC173 domain containing protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_142888 OG7: OG7_0007061 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510719.74
Mitochondrial large ribosomal subunit mL42, p
— Both
TcCLB.510351.40 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506635.20 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506739.90 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.507641.120 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507641.140 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.509267.90 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.508347.100
Domain of unknown function (DUF4460), putativ
— Both
TcCLB.507711.10
intraflagellar transport protein 57/55, putat
— Both
TcCLB.509831.50
intraflagellar transport protein 88, putative
— Both
TcCLB.484299.4 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
TcCLB.509825.14 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.442383.9 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.503757.10 ⚠
40S ribosomal protein SA, putative
— Both
TcCLB.503757.30
hypothetical protein, conserved
— Both
TcCLB.506211.40
intraflagellar transport protein 52
— Both
TcCLB.508323.20
Intraflagellar transport protein 74, putative
— Both
TcCLB.506895.30
Mitochondrial large ribosomal subunit mL85, p
— Both
TcCLB.509455.90
Putative intraflagellar transport protein A1
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.