TcCLB.507627.20

proton motive ATPase 1, putative

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100641 OG7: OG7_0001065 24 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 24 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.511041.40 ⚠ hexose transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
TcCLB.447255.29 ⚠ multidrug resistance-associated protein, puta	—	OG7 Tb927.10.12500 ↔ Tb927.4.4490 OG7 Tb927.10.12510 ↔ Tb927.4.4490 OG7 Tb927.10.12500 ↔ Tb927.8.2160 OG7 Tb927.10.12510 ↔ Tb927.8.2160	OG7
TcCLB.510231.29 ⚠ multidrug resistance-associated protein, puta	—	OG7 Tb927.10.12500 ↔ Tb927.4.4490 OG7 Tb927.10.12510 ↔ Tb927.4.4490 OG7 Tb927.10.12500 ↔ Tb927.8.2160 OG7 Tb927.10.12510 ↔ Tb927.8.2160	OG7
TcCLB.506529.380 ⚠ ser/thr protein phosphatase, putative	—	OG6 Tb927.1.4050 ↔ Tb927.10.12510 OG6 Tb927.1.4050 ↔ Tb927.10.12500	OG6
TcCLB.505789.20 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
TcCLB.505789.10 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
TcCLB.504111.40 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
TcCLB.509441.10 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
TcCLB.509835.30 ⚠ hypothetical protein, conserved	—	OG6 Tb11.1390 ↔ Tb927.10.12510 OG6 Tb11.1390 ↔ Tb927.10.12500 OG7 Tb11.1390 ↔ Tb927.10.12510 OG7 Tb11.1390 ↔ Tb927.10.12500	Both
TcCLB.506633.90 ⚠ folate/pteridine transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
TcCLB.510769.120 ⚠ calcium motive p-type ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.15460 OG6 Tb927.10.12510 ↔ Tb927.9.15460 OG7 Tb927.10.12500 ↔ Tb927.9.15460 OG7 Tb927.10.12510 ↔ Tb927.9.15460	Both
TcCLB.507093.260 ⚠ ABC transporter, mitochondrial, putative	—	OG6 Tb927.10.12500 ↔ Tb927.11.540 OG6 Tb927.10.12510 ↔ Tb927.11.540 OG7 Tb927.10.12500 ↔ Tb927.11.540 OG7 Tb927.10.12510 ↔ Tb927.11.540	Both
TcCLB.506649.20 ⚠ P-type H+-ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.12510 OG7 Tb927.10.12500 ↔ Tb927.10.12510	Both
TcCLB.505945.90 ⚠ folate/pteridine transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
TcCLB.504149.100 ⚠ Nodulin-like, putative	—	OG6 Tb927.10.12500 ↔ Tb927.11.6040 OG6 Tb927.10.12510 ↔ Tb927.11.6040	OG6
TcCLB.506249.70 ⚠ ATP-binding cassette protein subfamily G	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
TcCLB.508551.30 ⚠ hexose transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
TcCLB.506579.10 ⚠ ABC transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
TcCLB.504149.160 ⚠ phosphoinositide-specific phospholipase C, pu	—	OG6 Tb927.10.12500 ↔ Tb927.11.5970 OG6 Tb927.10.12510 ↔ Tb927.11.5970 OG7 Tb927.10.12500 ↔ Tb927.11.5970 OG7 Tb927.10.12510 ↔ Tb927.11.5970	Both
TcCLB.508551.39 ⚠ hexose transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.8530 OG6 Tb927.10.12510 ↔ Tb927.10.8530 OG7 Tb927.10.12500 ↔ Tb927.10.8530 OG7 Tb927.10.12510 ↔ Tb927.10.8530	Both
TcCLB.511575.130 ⚠ folate/pteridine transporter, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.9080 OG6 Tb927.10.12510 ↔ Tb927.10.9080 OG7 Tb927.10.12500 ↔ Tb927.10.9080 OG7 Tb927.10.12510 ↔ Tb927.10.9080	Both
TcCLB.504425.70 ⚠ hypothetical protein, conserved	—	OG6 Tb927.10.12500 ↔ Tb927.9.6310 OG6 Tb927.10.12510 ↔ Tb927.9.6310 OG6 Tb927.10.12500 ↔ Tb927.10.7700 OG6 Tb927.10.12510 ↔ Tb927.10.7700 +4 more	Both
TcCLB.507079.30 ⚠ multidrug resistance protein E, putative	—	OG6 Tb927.10.12500 ↔ Tb927.4.4490 OG6 Tb927.10.12510 ↔ Tb927.4.4490 OG6 Tb927.10.12500 ↔ Tb927.8.2160 OG6 Tb927.10.12510 ↔ Tb927.8.2160 +4 more	Both
TcCLB.509809.39 ⚠ P-type H+-ATPase, putative	—	OG6 Tb927.10.12500 ↔ Tb927.10.12510 OG7 Tb927.10.12500 ↔ Tb927.10.12510	Both