TcCLB.508229.50

hypothetical protein
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_118579 OG7: OG7_0022348 18 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 18 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508541.230 ⚠
casein kinase, putative
— OG6
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.503975.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506367.30 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
TcCLB.507873.60 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
TcCLB.511559.30 ⚠
ras-related GTP-binding protein, putative
— OG6
TcCLB.508207.74 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcCLB.504929.10 ⚠
casein kinase, delta isoform, putative
— OG6
TcCLB.508727.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.508541.220 ⚠
casein kinase, putative
— OG6
TcCLB.511741.40 ⚠
RNA-binding protein, putative
— OG6
TcCLB.503975.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.508215.10 ⚠
zinc finger CCCH domain containing protein 17
— Both
TcCLB.508207.70 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcCLB.508541.240 ⚠
casein kinase, putative
— OG6
TcCLB.508541.225 ⚠
casein kinase, putative
— OG6
TcCLB.508723.80 ⚠
disgorgin, putative
— Both
TcCLB.504929.15 ⚠
casein kinase, delta isoform, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.