TcIL3000_0_16560

2-hydroxy-3-oxopropionate reductase, putative
Trypanosoma congolense IL3000 OG6: OG6_101839 OG7: OG7_0002731 215 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 215 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_4160 ⚠
ubiquitin-like protein DSK2, putative
— OG7
TcIL3000_0_50890 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcIL3000_0_49160 ⚠
mitotic centromere-associated kinesin, putati
— OG7
TcIL3000_10_240 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_2530 ⚠
hypothetical protein, conserved, predicted to
— OG7
TcIL3000_2_1280 ⚠
aldo-keto reductase, putative
— OG7
TcIL3000_2_800 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000_10_2690 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_5690 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_5120 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_2860 ⚠
Mitochondrial ATP synthase subunit, putative
— OG7
TcIL3000_0_08900 ⚠
hypothetical protein
— OG7
TcIL3000_8_5670 ⚠
50S ribosomal protein L17, putative
— OG7
TcIL3000_5_3200 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_29200 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_1670 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_32600 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.4740 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.4730 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_58910 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_4_3480 ⚠
Kinesin-13 4, putative
— OG7
TcIL3000.11.10570 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_24550 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.4760 ⚠
Kinesin-13 2, putative
— OG7
TcIL3000_9_1140 ⚠
Kinesin-13 1, putative
— OG7
TcIL3000.11.3100 ⚠
Kinesin-13 5, putative
— OG7
TcIL3000_0_42700 ⚠
alanine racemase, putative
— Both
TcIL3000_0_55160 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_10_7700 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.10800 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— Both
TcIL3000_9_5750 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_0_26440 ⚠
hypothetical protein, conserved
— Both
TcIL3000_9_5740 ⚠
Importin 1 (fragment)
— Both
TcIL3000_3_1280 ⚠
translation elongation factor EF-2, putative
— Both
TcIL3000.11.8960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcIL3000.11.5260 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcIL3000_10_2990 ⚠
aspartate aminotransferase, putative
— Both
TcIL3000.11.8170 ⚠
predicted WD40 repeat protein
— Both
TcIL3000_8_5510 ⚠
Met-10+ like-protein, putative
— Both
TcIL3000_0_14770 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcIL3000_4_3320 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000.11.1410 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.8770 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_50720 ⚠
PWWP domain/TFIIS helical bundle-like domain
— Both
TcIL3000_0_44700 ⚠
transcription elongation factor s-II, putativ
— Both
TcIL3000_0_29070 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_0_32960 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_5_1300 ⚠
alanine racemase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.