TcIL3000_0_27180

1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase, putative
Trypanosoma congolense IL3000 OG6: OG6_139725 OG7: OG7_0005923 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_32550 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcIL3000_7_1260 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcIL3000.11.10520 ⚠
Charged multivesicular body protein 3, putati
— OG7
TcIL3000_10_2000 ⚠
casein kinase I, putative (fragment)
— OG7
TcIL3000_7_570 ⚠
zinc finger CCCH domain containing protein 17
— OG7
TcIL3000_0_49340 ⚠
zinc finger CCCH domain containing protein 13
— OG7
TcIL3000_10_7540 ⚠
GTPase activating protein, putative
— OG7
TcIL3000_6_4390 ⚠
Zinc finger CCCH domain-containing protein 47
— OG7
TcIL3000_0_32110 ⚠
casein kinase I, isoform 2
— OG7
TcIL3000_0_17490 ⚠
Protein kinase domain containing protein, put
— OG7
TcIL3000.11.1820 ⚠
Snf7, putative
— OG7
TcIL3000_9_2080 ⚠
PTP1-interacting protein, 39 kDa
— OG7
TcIL3000_0_59030 ⚠
NUDIX hydrolase, conserved (fragment)
— OG7
TcIL3000_0_25090 ⚠
zinc finger CCCH domain containing protein 12
— OG7
TcIL3000_10_7530 ⚠
GTPase activating protein, putative
— OG7
TcIL3000_4_1320 ⚠
protein kinase, putative
— OG7
TcIL3000_3_730 ⚠
casein kinase 1, putative
— OG7
TcIL3000_5_440 ⚠
casein kinase I, epsilon isoform, putative
— OG7
TcIL3000.11.5420 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_13070 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_480 ⚠
casein kinase, putative
— OG7
TcIL3000_0_37550 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcIL3000_4_3220 ⚠
Uncharacterized conserved protein (DUF2039),
— OG7
TcIL3000_8_3950 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_3940 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_33080 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_630 ⚠
serine-palmitoyl-CoA transferase, putative
— OG7
TcIL3000_10_3380 ⚠
serine palmitoyltransferase, putative
— OG7
TcIL3000_0_29070 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000.11.15820 ⚠
iron superoxide dismutase
— Both
TcIL3000.11.15220 ⚠
iron superoxide dismutase
— Both
TcIL3000.11.15750 ⚠
superoxide dismutase, putative
— Both
TcIL3000.11.15560 ⚠
heat shock protein Hsp20, putative
— Both
TcIL3000_8_6020 ⚠
transketolase, putative
— Both
TcIL3000_8_2050
arginase, putative
— OG6
TcIL3000_9_3590
peptidyl-prolyl cis-trans isomerase (cyclophi
— OG6
TcIL3000_10_12130 ⚠
N-myristoyl transferase, putative
— Both
TcIL3000_3_1350 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
TcIL3000_8_5850 ⚠
glycine acetyltransferase, putative, 2-amino-
— Both
TcIL3000_4_3320 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_0_32960 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_0_17500 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcIL3000_0_37540 ⚠
Protein kinase domain containing protein, put
— OG7
TcIL3000_5_1490 ⚠
zinc finger CCCH domain containing protein 12
— OG7
TcIL3000.11.10300 ⚠
NUDIX hydrolase 3, putative
— OG7
TcIL3000_3_50 ⚠
zinc finger protein 2, putative
— OG7
TcIL3000_10_7440 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_57260 ⚠
nucleoside 2-deoxyribosyltransferase
— OG7
TcIL3000_0_29990 ⚠
nucleoside 2-deoxyribosyltransferase
— OG7
TcIL3000_0_52880 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.