TcIL3000_10_5200

neurobeachin/beige protein, putative
Trypanosoma congolense IL3000 OG6: OG6_101577 OG7: OG7_0001358 270 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 270 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_03440 ⚠
pyridine nucleotide-disulphide oxidoreductase
— OG7
TcIL3000.11.6810 ⚠
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— OG7
TcIL3000_0_42340 ⚠
cytoskeleton-associated protein, putative (fr
— OG7
TcIL3000.11.1160 ⚠
Domain of unknown function (DUF4470)/Domain o
— OG7
TcIL3000.11.4180 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_2350 ⚠
START domain containing protein, putative
— OG7
TcIL3000_6_2620 ⚠
microtubule associated protein xmap215
— OG7
TcIL3000_10_5470 ⚠
chaperonin HSP60, mitochondrial precursor
— OG7
TcIL3000_10_5580 ⚠
chaperonin HSP60, mitochondrial precursor
— OG7
TcIL3000_9_3140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcIL3000_7_5240 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_3500 ⚠
chaperonin HSP60, mitochondrial precursor, pu
— OG7
TcIL3000_0_09430 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.2950 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_50920 ⚠
cytoskeleton-associated protein, putative
— OG7
TcIL3000.11.10010 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_4870 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcIL3000_0_33050 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000.11.620 ⚠
RNA polymerase I second largest subunit (frag
— OG7
TcIL3000.11.11340 ⚠
glycosyl hydrolase, putative
— OG7
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— OG7
TcIL3000_7_460 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.1300 ⚠
Right handed beta helix region/Periplasmic co
— OG7
TcIL3000_6_1240 ⚠
ubiquitin hydrolase, putative
— OG7
TcIL3000_0_52930 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000.11.11680 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— OG7
TcIL3000_4_2790 ⚠
Nucleoporin
— OG7
TcIL3000_0_19850 ⚠
acetyl-CoA carboxylase
— OG7
TcIL3000_8_7160 ⚠
acetyl-CoA carboxylase
— OG7
TcIL3000_3_510 ⚠
PRP38 family, putative
— OG7
TcIL3000_0_34510 ⚠
hypothetical protein
— OG7
TcIL3000_0_57110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_4_3350 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000.11.6110 ⚠
formin-like protein
— OG7
TcIL3000.11.290 ⚠
RNA-binding protein, putative
— OG7
TcIL3000_0_38480 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000.11.11300 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— OG7
TcIL3000_0_21140 ⚠
Right handed beta helix region containing pro
— OG7
TcIL3000.11.610 ⚠
RNA polymerase I second largest subunit (frag
— OG7
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG7
TcIL3000.11.9050 ⚠
Cell division control protein 48, putative
— OG7
TcIL3000_0_48570 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_9940 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_110 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcIL3000_7_4310 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_5_1110 ⚠
exosome component CSL4, putative
— OG7
TcIL3000_0_21910 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.