TcIL3000_10_8190

phosphoribosylpyrophosphate synthetase, putative
Trypanosoma congolense IL3000 OG6: OG6_100356 OG7: OG7_0002319 200 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 200 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_8_7160 ⚠
acetyl-CoA carboxylase
— +6 more Both
TcIL3000_0_19850 ⚠
acetyl-CoA carboxylase
— +6 more Both
TcIL3000.11.2790 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +4 more Both
TcIL3000_0_33050 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
TcIL3000_10_2390 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcIL3000_0_60440 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
TcIL3000_8_4870 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcIL3000_4_4270 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_10_9940 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_41600 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_10_13390 ⚠
zinc finger protein, putative
— OG7
TcIL3000.11.14960 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcIL3000_8_3410 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcIL3000_10_11370 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_7870 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_37380 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_7280 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcIL3000_1_1110 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcIL3000_8_3720 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_22520 ⚠
histone deacetylase, putative
— OG7
TcIL3000_0_50360 ⚠
histone deacetylase 2 (fragment)
— OG7
TcIL3000_7_3400 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcIL3000_10_11380 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_8_2740 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_9_5660 ⚠
hypothetical protein
— OG7
TcIL3000_9_2920 ⚠
adenylate kinase, putative
— OG7
TcIL3000.11.290 ⚠
RNA-binding protein, putative
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_10_2630 ⚠
ABC transporter, putative
— OG7
TcIL3000_4_3460 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_6450 ⚠
cullin, putative
— OG7
TcIL3000_10_9170 ⚠
protein kinase, putative
— OG7
TcIL3000_4_110 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcIL3000_7_4310 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_9_5860 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_4_820 ⚠
hypothetical protein
— OG7
TcIL3000_0_44990 ⚠
Right handed beta helix region containing pro
— OG7
TcIL3000_0_21910 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.9050 ⚠
Cell division control protein 48, putative
— OG7
TcIL3000_0_38480 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_0_22450 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.11300 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000.11.14900 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcIL3000_8_3570 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.