TcIL3000_5_4300 – TrypsnetDB2

TcIL3000_5_4300

dihydroorotate dehydrogenase, putative

Trypanosoma congolense IL3000 OG6: OG6_100674 OG7: OG7_0005744 18 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 18 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_0_03190 ⚠ E2-like ubiquitin-conjugation enzyme	—	OG6 TCSYLVIO_001047 ↔ TCSYLVIO_001184 OG7 TCSYLVIO_001047 ↔ TCSYLVIO_001184	Both
TcIL3000_0_00820 ⚠ FAD binding domain/Oxidoreductase NAD-binding	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7
TcIL3000_0_20750 ⚠ NADPH-cytochrome p450 reductase, putative (fr	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7
TcIL3000_0_54440 ⚠ NADPH-cytochrome p450 reductase, putative	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7
TcIL3000_3_2070 ⚠ poly(A) polymerase, putative	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_010610	OG7
TcIL3000_9_5590 ⚠ NADPH--cytochrome p450 reductase, putative (f	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7
TcIL3000_0_21240 ⚠ pyridoxal kinase	—	OG6 Tb927.5.3830 ↔ Tb927.6.2740 OG7 Tb927.5.3830 ↔ Tb927.6.2740	Both
TcIL3000_6_2200 ⚠ hypothetical protein (fragment)	—	OG6 Tb927.5.3830 ↔ Tb927.6.2740 OG7 Tb927.5.3830 ↔ Tb927.6.2740	Both
TcIL3000_2_90 ⚠ Autophagocytosis associated protein (Atg3), N	—	OG6 TCSYLVIO_001047 ↔ TCSYLVIO_001184 OG7 TCSYLVIO_001047 ↔ TCSYLVIO_001184	Both
TcIL3000.11.5260 ⚠ aspartate aminotransferase, mitochondrial, pu	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005115 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005115	Both
TcIL3000_0_09690 ⚠ E2-like ubiquitin-conjugation enzyme	—	OG6 TCSYLVIO_001047 ↔ TCSYLVIO_001184 OG7 TCSYLVIO_001047 ↔ TCSYLVIO_001184	Both
TcIL3000_3_1870 inosine-adenosine-guanosine-nucleosidehydrola	—	OG6 Tb927.3.2960 ↔ Tb927.5.3830 OG7 Tb927.3.2960 ↔ Tb927.5.3830	Both
TcIL3000_4_1680 ⚠ NADPH--cytochrome P450 reductase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_003840 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	Both
TcIL3000_0_42480 hypothetical protein, conserved	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_004409 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_004409	Both
TcIL3000_10_2990 ⚠ aspartate aminotransferase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005115 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005115	Both
TcIL3000_7_3040 ⚠ poly(A) polymerase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_010610 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_010610	Both
TcIL3000_8_240 ⚠ PPIase, putative, peptidyl-prolyl cis-trans i	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG6
TcIL3000_0_36940 nitrilase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005176 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005176	Both

Orthogroup expansion — connections between the query proteins

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