TcIL3000_8_4270

Eukaryotic translation initiation factor 4 gamma 5
Trypanosoma congolense IL3000 OG6: OG6_139892 OG7: OG7_0037732 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.14880
G5-interacting protein
— Both
TcIL3000_0_06320 ⚠
cyclophilin a, putative
— OG6
TcIL3000_6_390
ccr4-not transcription complex subunit 2
— Both
TcIL3000.11.7270 ⚠
mRNA cap guanine-N7 methyltransferase, putati
— Both
TcIL3000_0_51130 ⚠
mRNA cap guanine-N7 methyltransferase, putati
— Both
TcIL3000_10_7090
Ribosomal protein L1p/L10e family, putative
— Both
TcIL3000_10_1310
CCR4-NOT transcription complex subunit 1
— Both
TcIL3000_0_06960 ⚠
mRNA cap guanine-N7 methyltransferase, putati
— Both
TcIL3000_0_19500 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcIL3000_9_1280 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcIL3000_5_2960
Beta-lactamase superfamily domain containing
— Both
TcIL3000_0_46480 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000.11.810 ⚠
cyclophilin a, putative
— OG6
TcIL3000_8_2030 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TcIL3000_0_06330 ⚠
cyclophilin a, putative
— OG6
TcIL3000_0_45310
Mitochondrial outer membrane protein porin, p
— Both
TcIL3000_0_51370 ⚠
Eukaryotic translation initiation factor 4E t
— Both
TcIL3000_7_1220 ⚠
Eukaryotic translation initiation factor 4E t
— Both
TcIL3000_7_2140 ⚠
histone H2A, putative
— Both
TcIL3000_0_01220
cAMP-specific phosphodiesterase, putative
— Both
TcIL3000_9_2670 ⚠
DENN (AEX-3) domain containing protein, putat
— Both
TcIL3000_0_51380 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_1820 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TcIL3000_7_4020
hypothetical protein, conserved
— OG7
TcIL3000_4_950 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
TcIL3000_0_31970 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_10_1290 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcIL3000.11.5490 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000.11.5520 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_33690
Kinetochore interacting protein 5
— OG7
TcIL3000_9_620
hypothetical protein, conserved
— OG7
TcIL3000_0_02310 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_10_10740
Protein of unknown function (DUF3648), putati
— OG7
TcIL3000.11.13430 ⚠
translation-associated element 2, putative
— Both
TcIL3000_10_7470
hypothetical protein, conserved
— OG7
TcIL3000_7_5200 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000.11.13700 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_05900 ⚠
Skp1 family, dimerisation domain containing p
— OG7
TcIL3000.11.13690 ⚠
Skp1 family, dimerisation domain containing p
— OG7
TcIL3000_7_5270 ⚠
histone H2A variant Z
— OG7
TcIL3000_0_24190 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_09950 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_55460 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_45960 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_9_2130
protein phosphatase 2A regulatory subunit, pu
— Both
TcIL3000_0_52960 ⚠
Docking domain of Afi1 for Arf3 in vesicle tr
— Both
TcIL3000_0_47590 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_10_2330 ⚠
hypothetical protein, conserved, predicted WD
— Both
TcIL3000_0_47000 ⚠
IQ calmodulin-binding motif containing protei
— Both
TcIL3000_6_3400 ⚠
Docking domain of Afi1 for Arf3 in vesicle tr
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.