TcYC6_0030400

Ring finger domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_156425 OG7: OG7_0000431 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0081520
Kinesin-13 3, putative
— OG6
TcYC6_0115840
PA26 p53-induced protein (sestrin), putative
— OG6
TcYC6_0088110
Shwachman-Bodian-Diamond syndrome (SBDS) prot
— OG6
TcYC6_0045500
hypothetical protein, conserved
— OG6
TcYC6_0098370
Protein of unknown function (DUF544), putativ
— OG6
TcYC6_0000250
Gar1/Naf1 RNA binding region, putative
— OG6
TcYC6_0082740
STE/STE11 serine/threonine-protein kinase, pu
— OG6
TcYC6_0110270
protein farnesyltransferase alpha subunit, pu
— OG6
TcYC6_0054390
Met-10+ like-protein, putative
— OG6
TcYC6_0077150
NEDD8-activating enzyme E1 regulatory subunit
— OG6
TcYC6_0096900
hypothetical protein
— OG6
TcYC6_0096590
pseudouridine synthase A-like protein, putati
— OG6
TcYC6_0016790
cyclophilin 15, putative
— OG6
TcYC6_0116790 ⚠
pumilio/PUF RNA binding protein 2, putative
— OG6
TcYC6_0079270 ⚠
putative pumilio/PUF RNA binding protein 6
— OG6
TcYC6_0031370
5'-AMP-activated protein kinase subunit beta,
— OG6
TcYC6_0098750 ⚠
calmodulin, putative
— OG6
TcYC6_0072130
hypothetical protein
— OG6
TcYC6_0053230
HECT-domain (ubiquitin-transferase), putative
— OG6
TcYC6_0067370 ⚠
hypothetical protein
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.