TcYC6_0031970

putative multidrug resistance protein E
Trypanosoma cruzi Y C6 OG6: OG6_100026 OG7: OG7_0000689 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0073870 ⚠
hypothetical protein, conserved
— Both
TcYC6_0075190 ⚠
ABC transporter, mitochondrial, putative
— Both
TcYC6_0110300 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0070710 ⚠
Flagellum attachment zone protein 4
— Both
TcYC6_0106710 ⚠
monoglyceride lipase, putative
— Both
TcYC6_0106780 ⚠
monoglyceride lipase, putative
— Both
TcYC6_0106750 ⚠
monoglyceride lipase, putative
— Both
TcYC6_0060350 ⚠
ser/thr protein phosphatase, putative
— OG6
TcYC6_0080000 ⚠
hypothetical protein, conserved
— Both
TcYC6_0073880 ⚠
hypothetical protein, conserved
— Both
TcYC6_0082830 ⚠
hypothetical protein, conserved
— Both
TcYC6_0082960 ⚠
hypothetical protein, conserved
— Both
TcYC6_0082900 ⚠
hypothetical protein, conserved
— Both
TcYC6_0082810 ⚠
hypothetical protein, conserved
— Both
TcYC6_0116900 ⚠
P-type H+-ATPase, putative
— +4 more Both
TcYC6_0113940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0080960 ⚠
copper homeostasis protein, putative
— Both
TcYC6_0043000 ⚠
hypothetical protein
— OG6
TcYC6_0005420 ⚠
soluble N-ethylmaleimide sensitive factor (NS
— Both
TcYC6_0050660 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
TcYC6_0008870 ⚠
protein phosphatase 1, regulatory subunit, pu
— Both
TcYC6_0086000 ⚠
hypothetical protein, conserved
— Both
TcYC6_0089200 ⚠
multidrug resistance-associated protein, puta
— OG7
TcYC6_0067300 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0014070 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0108160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0052650 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0027960 ⚠
ABC transporter
— +4 more Both
TcYC6_0060430 ⚠
Fusaric acid resistance protein-like, putativ
— Both
TcYC6_0032330 ⚠
putative multidrug resistance protein E
— Both
TcYC6_0033300 ⚠
multidrug resistance protein A,p-glycoprotein
— Both
TcYC6_0106570 ⚠
putative multidrug resistance protein E
— Both
TcYC6_0032200 ⚠
putative multidrug resistance protein E
— Both
TcYC6_0032190 ⚠
putative multidrug resistance-associated prot
— Both
TcYC6_0032760 ⚠
multidrug resistance protein A,multidrug resi
— Both
TcYC6_0154180 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0027840 ⚠
putative ABC transporter
— +4 more Both
TcYC6_0067320 ⚠
calcium motive p-type ATPase, putative
— Both
TcYC6_0127660 ⚠
ATP-binding cassette protein, putative
— +4 more Both
TcYC6_0031450 ⚠
ABC transporter, putative
— +4 more Both
TcYC6_0042910 ⚠
phosphoinositide-specific phospholipase C
— Both
TcYC6_0027920 ⚠
ABC transporter
— +4 more Both
TcYC6_0027880 ⚠
ABC transporter
— +4 more Both
TcYC6_0154310 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0121820 ⚠
ATP-binding cassette protein subfamily G
— +4 more Both
TcYC6_0053080 ⚠
ADP-ribosylation factor GTPase activating pro
— Both
TcYC6_0025450 ⚠
P-type H+-ATPase
— +4 more Both
TcYC6_0117000 ⚠
P-type H+-ATPase, putative
— +4 more Both
TcYC6_0116910 ⚠
P-type H+-ATPase, putative
— +4 more Both
TcYC6_0116930 ⚠
P-type H+-ATPase, putative
— +4 more Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.