TvY486_0403680

Calpain-like protein 2
Trypanosoma vivax Y486 OG6: OG6_156861 OG7: OG7_0001161 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1101010 ⚠
antigen GM6, putative, (fragment)
— OG6
TvY486_1101000 ⚠
calpain, putative, (fragment)
— OG6
TvY486_0045390 ⚠
calpain-like cysteine peptidase, putative, (f
— OG6
TvY486_1101020 ⚠
calpain-like cysteine peptidase, putative, (f
— OG6
TvY486_1100990 ⚠
cytoskeleton assocociated protein, putative,
— OG6
TvY486_1000160 ⚠
60S ribosomal proteins L37, putative
— OG6
TvY486_1112230 ⚠
40S ribosomal protein L14, putative
— OG6
TvY486_1006330 ⚠
60S ribosomal proteins L37, putative
— OG6
TvY486_0804980
hypothetical protein, conserved
— OG6
TvY486_0304890
Putative intraflagellar transport protein B2
— OG6
TvY486_1110760 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— OG6
TvY486_1005370
40S ribosomal protein S18, putative
— OG6
TvY486_0903870 ⚠
60S ribosomal protein L37, putative
— OG6
TvY486_1111690 ⚠
40S ribosomal protein SA, putative, (fragment
— OG6
TvY486_1115080
Dynein intermediate chain, axonemal
— OG6
TvY486_1103060 ⚠
60S ribosomal protein L37, putative, (fragmen
— OG6
TvY486_1011200 ⚠
40S ribosomal protein S3, putative
— OG6
TvY486_0902250 ⚠
40S ribosomal protein S3, putative
— OG6
TvY486_1111700 ⚠
40S ribosomal protein SA, putative
— OG6
TvY486_0905810 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TvY486_0403320 ⚠
60S ribosomal protein L13a, putative
— OG6
TvY486_1101420 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— OG6
TvY486_0905800 ⚠
60S ribosomal subunit protein, putative
— OG6
TvY486_0401580
ribosomal protein S19, putative
— OG6
TvY486_0501090 ⚠
60S ribosomal protein L13a, putative
— OG6
TvY486_0200510
hypothetical protein, conserved
— OG6
TvY486_0600230 ⚠
40S ribosomal protein L14, putative
— OG6
TvY486_1102540 ⚠
Unc104-like kinesin, putative, (fragment)
— OG6
TvY486_0304940 ⚠
Tb-292 membrane associated protein, (fragment
— OG6
TvY486_0024020 ⚠
Tb-292 membrane associated protein, putative
— OG6
TvY486_0011040 ⚠
60S ribosomal protein L7, putative (fragment)
— OG6
TvY486_0011050 ⚠
60S ribosomal protein L7, putative
— OG6
TvY486_0701610 ⚠
60S ribosomal protein L7, putative
— OG6
TvY486_0011060 ⚠
60S ribosomal protein L7, putative
— OG6
TvY486_0201830
hypothetical protein, conserved
— OG6
TvY486_0300120
zinc finger protein 2, putative
— OG6
TvY486_1012380
hypothetical protein, conserved
— OG6
TvY486_1107550
GRIP domain containing protein, putative
— OG6
TvY486_0004990 ⚠
kinesin, putative (fragment)
— OG6
TvY486_1103730 ⚠
40S ribosomal protein S4, putative
— OG6
TvY486_0400130
proteasome beta 7 subunit
— OG6
TvY486_0806920 ⚠
symplekin
— OG6
TvY486_0404270 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_0800730 ⚠
60S ribosomal protein L7a, putative
— OG6
TvY486_0800740 ⚠
60S ribosomal protein L7a, putative
— OG6
TvY486_0302680 ⚠
60S ribosomal protein L13, putative
— OG6
TvY486_0302690 ⚠
60S ribosomal protein L13, putative
— OG6
TvY486_0025890
hypothetical protein, conserved
— OG6
TvY486_1012010
hypothetical protein, conserved
— OG6
TvY486_1103720 ⚠
40S ribosomal protein S4, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.