TvY486_0801250

pitrilysin-like metalloprotease, putative, metallo-peptidase, Clan ME, Family M16C, putative
Trypanosoma vivax Y486 OG6: OG6_101809 OG7: OG7_0004979 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1001120 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TvY486_0400910 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TvY486_0503300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TvY486_0802360 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_0011310 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_0017320
tyrosine aminotransferase
— Both
TvY486_0304430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
TvY486_0502060
otubain cysteine peptidase, Clan CA, family C
— Both
TvY486_0301950
TatD related DNase, putative
— Both
TvY486_1010390
iron-containing hydrogenase, putative
— Both
TvY486_1109070 ⚠
ribonuclease II-like protein, putative, (frag
— OG7
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_1012450 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TvY486_1012430 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TvY486_1102100 ⚠
choline/ethanolamine kinase, putative
— OG7
TvY486_0903710 ⚠
GTP-binding protein, putative
— OG7
TvY486_1104200 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
TvY486_0700310 ⚠
GTP-binding protein, putative
— OG7
TvY486_0903790 ⚠
GTP-binding protein, putative
— OG7
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0042910 ⚠
GTP-binding protein, putative
— OG7
TvY486_1102700 ⚠
GTPase protein, putative
— OG7
TvY486_0500660 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TvY486_1114000 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1111190 ⚠
regulator of chromosome condensation 1-like p
— OG7
TvY486_0703360 ⚠
p22 protein precursor, putative
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_1115120 ⚠
ubiquitin transferase, (fragment)
— OG7
TvY486_1111150 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_1107120 ⚠
regulator of chromatin condensation, putative
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_0603050
hypothetical protein, conserved
— OG7
TvY486_0019440 ⚠
p22 protein precursor, putative
— OG7
TvY486_0701030 ⚠
regulator of chromosome condensation, putativ
— OG7
TvY486_1010490 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0402970 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TvY486_0503310 ⚠
tubulin tyrosine ligase, putative, (fragment)
— OG7
TvY486_0021890 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0900600
hypothetical protein, conserved
— OG7
TvY486_0706370 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG7
TvY486_1013420 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_0803350
oxidoreductase, putative
— OG7
TvY486_0906450 ⚠
ankyrin repeat protein, putative
— OG7
TvY486_0706880 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TvY486_1012640 ⚠
hypothetical protein, conserved
— OG7
TvY486_0701050 ⚠
hypothetical protein, conserved
— OG7
TvY486_1101390
hypothetical protein, conserved
— OG7
TvY486_0804060 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.