TvY486_1116230

NADH-ubiquinone oxidoreductase complex I subunit, putative
Trypanosoma vivax Y486 OG6: OG6_142827 OG7: OG7_0043530 23 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 23 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1104610
long-chain-fatty-acid-CoA ligase, putative
— Both
TvY486_0804250 ⚠
prohibitin, (fragment)
— OG7
TvY486_1005530
hypothetical protein, conserved
— Both
TvY486_1004290 ⚠
prohibitin, putative
— Both
TvY486_1014270
Complex 1 protein (LYR family), putative
— Both
TvY486_0805080
hypothetical protein, conserved
— Both
TvY486_0404590
hypothetical protein, conserved
— Both
TvY486_0502730
hypothetical protein, conserved
— Both
TvY486_0400140
NADH:ubiquinone oxidoreductase, ESSS subunit,
— Both
TvY486_0900060
Monooxygenase, putative
— Both
TvY486_0904450
hypothetical protein, conserved
— Both
TvY486_0905380
hypothetical protein, conserved
— Both
TvY486_0802000
hypothetical protein, conserved
— Both
TvY486_0703900
hypothetical protein, conserved
— Both
TvY486_0902540
flavoprotein monooxygenase, putative
— Both
TvY486_0907350
hypothetical protein, conserved
— Both
TvY486_1116630
NADH dehydrogenase subunit NI2M, putative
— Both
TvY486_0300270
acyl carrier protein, mitochondrial, putative
— Both
TvY486_0807330
hypothetical protein, conserved
— Both
TvY486_1110710
hypothetical protein, conserved
— Both
TvY486_0300760
ATP synthase subunit beta, mitochondrial, put
— Both
TvY486_1102740
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TvY486_0500120
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.